{"id":"W2038987291","doi":"10.1007/s10048-007-0103-3","title":"Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer’s disease","year":2007,"lang":"en","type":"article","venue":"Neurogenetics","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Health Canada; National Institute on Aging; National Institutes of Health; Wellcome Trust","keywords":"Human genetics; Linkage (software); Age of onset; Disease; Medicine; Early-onset Alzheimer's disease; Genetic linkage; Demography; Alzheimer's disease; Genetics; Pediatrics; Gerontology; Internal medicine; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000367433,0.0002456421,0.0003575629,0.0005176523,0.00008932241,0.00003219723,0.000156026,0.00008813364,0.0001697188],"category_scores_gemma":[0.00008237649,0.0002142971,0.0001732308,0.001221284,0.0001587764,0.00003113957,0.0001373478,0.0003251758,0.00005484364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007819995,"about_ca_system_score_gemma":0.0001767249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000711711,"about_ca_topic_score_gemma":0.001157697,"domain_scores_codex":[0.9976078,0.0001093322,0.0003635517,0.0004945874,0.0007641425,0.0006605834],"domain_scores_gemma":[0.9985679,0.0001160229,0.00006966147,0.0005075344,0.0001433673,0.0005955453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009741659,0.0003873934,0.9903744,0.00002367441,0.0004531047,0.004858904,0.00009949928,0.0000772939,0.0006627575,0.000003819688,0.0002222505,0.001862721],"study_design_scores_gemma":[0.001800767,0.0005746224,0.9863722,0.0000206944,0.002532948,0.00002666869,0.00005174487,0.0009135193,0.005294183,0.00001327051,0.002200333,0.0001990094],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972907,0.000459347,0.0002520902,0.0003245271,0.00006079975,0.0005909855,0.00009221454,0.00004889294,0.0008804386],"genre_scores_gemma":[0.997336,0.0002135981,0.0002934181,0.001049834,0.00005927001,0.00001839908,0.0002997392,0.00004325577,0.0006864665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004832236,"threshold_uncertainty_score":0.8738782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02362755699119699,"score_gpt":0.3062586519473325,"score_spread":0.2826310949561355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}