{"id":"W2038996283","doi":"10.1080/03630260701284624","title":"Three New β-Globin Gene Promoter Mutations Identified Through Newborn Screening","year":2007,"lang":"en","type":"article","venue":"Hemoglobin","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Hamilton Regional Laboratory Medicine Program; Hamilton Health Sciences","funders":"","keywords":"Gene; Genetics; Biology; Globin; Molecular biology; Mutation; Sequence (biology); Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004171405,0.0003564533,0.0004375059,0.0001735905,0.0002597301,0.00006830382,0.0001959758,0.0003657504,0.0009541181],"category_scores_gemma":[0.00009445968,0.0003175435,0.0002649015,0.0008110231,0.0001157018,0.0002445155,0.00009634567,0.0005023041,0.0006244864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001282449,"about_ca_system_score_gemma":0.0002439085,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001032211,"about_ca_topic_score_gemma":0.0002234333,"domain_scores_codex":[0.9973124,0.00002274268,0.0006648359,0.0006047393,0.0005341238,0.0008611123],"domain_scores_gemma":[0.9985756,0.00006734771,0.0001533156,0.000581653,0.000152088,0.0004699976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001235849,0.001155363,0.02015379,0.0002402189,0.001023178,0.00266309,0.006183608,0.0002739371,0.06417616,0.005704775,0.1301455,0.7670445],"study_design_scores_gemma":[0.03197288,0.001751755,0.2354227,0.001531607,0.002098826,0.00599188,0.00689151,0.004322908,0.1476461,0.01999592,0.5389703,0.00340357],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2058219,0.001526244,0.7585496,0.003924619,0.0007592623,0.001250397,0.00001531117,0.0004575163,0.02769521],"genre_scores_gemma":[0.5082693,0.0001213665,0.4604707,0.004882843,0.001471101,0.00004297813,0.0004398528,0.0002471987,0.02405471],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.7636409,"threshold_uncertainty_score":0.9999592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02679901191354043,"score_gpt":0.2869888150181839,"score_spread":0.2601898031046435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}