{"id":"W2039014355","doi":"10.1021/om700849w","title":"A Mechanism Displaying Autocatalysis:  The Hydrogenation of Acetophenone Catalyzed by RuH(<i>S</i>-binap)(app) Where app Is the Amido Ligand Derived from 2-Amino-2-(2-pyridyl)propane","year":2007,"lang":"en","type":"article","venue":"Organometallics","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; BINAP; Acetophenone; Catalysis; Medicinal chemistry; Ruthenium; Ligand (biochemistry); Hydride; Pyridine; Stereochemistry; Organic chemistry; Enantioselective synthesis; Hydrogen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009613476,0.0005230898,0.0006619637,0.0002095156,0.000535462,0.0001405105,0.001275651,0.0003329051,0.001360364],"category_scores_gemma":[0.0002235057,0.0003572805,0.0004156082,0.002100455,0.0002787261,0.0002659594,0.0003289685,0.0004626207,0.0001516918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002015863,"about_ca_system_score_gemma":0.0001035084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004814369,"about_ca_topic_score_gemma":0.0001397141,"domain_scores_codex":[0.9964193,0.00006023526,0.001026897,0.0007429,0.00114119,0.0006095051],"domain_scores_gemma":[0.9968166,0.0004502337,0.0008317392,0.001449983,0.0002422455,0.0002092219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004792207,0.0002520311,0.0002278981,0.00007776901,0.001000764,0.00001005411,0.002864306,0.0000138189,0.987605,0.0004198794,0.0003549897,0.007125576],"study_design_scores_gemma":[0.0009750237,0.00001649992,0.000161764,0.00003087067,0.0008486498,0.00001296243,0.002807625,0.001253291,0.9875525,0.0004357718,0.00546342,0.0004416365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846019,0.003378229,0.00769549,0.001067182,0.0001030733,0.0003561923,0.0003629767,0.00020606,0.002228969],"genre_scores_gemma":[0.9949573,0.0004019811,0.0002350572,0.0003332043,0.0001654093,0.00005958273,0.001039147,0.0001027532,0.00270555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01035549,"threshold_uncertainty_score":0.9998879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008030147949366705,"score_gpt":0.2149553319821013,"score_spread":0.2069251840327345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}