{"id":"W2039014355","doi":"10.1021/om700849w","title":"A Mechanism Displaying Autocatalysis:  The Hydrogenation of Acetophenone Catalyzed by RuH(<i>S</i>-binap)(app) Where app Is the Amido Ligand Derived from 2-Amino-2-(2-pyridyl)propane","year":2007,"lang":"en","type":"article","venue":"Organometallics","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; BINAP; Acetophenone; Catalysis; Medicinal chemistry; Ruthenium; Ligand (biochemistry); Hydride; Pyridine; Stereochemistry; Organic chemistry; Enantioselective synthesis; Hydrogen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009911889,0.0004433704,0.0002286922,0.0001397288,0.0001364428,0.00032419,0.0006370904,0.000446366,0.001688247],"category_scores_gemma":[0.0001372786,0.0002241427,0.0002593488,0.0000639516,0.0003986481,0.0005775006,0.0003377321,0.0004002488,0.0004400507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002447554,"about_ca_system_score_gemma":0.0001257989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003450206,"about_ca_topic_score_gemma":0.0002663087,"domain_scores_codex":[0.9999033,0.00001346692,0.000004354426,0.00002233359,0.00002597714,0.00003047113],"domain_scores_gemma":[0.9999423,0.00001468974,0.0000126199,0.00001039676,0.00000743372,0.00001256793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008042388,0.00005193715,0.0003028325,0.000197199,0.00001961685,0.0004169134,0.00005254821,0.0003442365,0.9931206,0.00234648,0.0002142505,0.002852913],"study_design_scores_gemma":[0.00001968747,0.0001309941,0.0008429554,0.000003871926,0.000009502432,0.0004280526,0.00002252655,0.003707641,0.9930616,0.0004501883,0.001313648,0.000009377459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9694942,0.001534859,0.01988229,0.0004121969,0.000129626,0.0001656216,0.0002463431,0.001039478,0.007095405],"genre_scores_gemma":[0.9966897,0.0002944828,0.00129493,0.00003064431,0.00000822025,0.00003317709,0.00004025864,0.000009747434,0.001598738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001688247,"threshold_uncertainty_score":0.005647719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008030147949366705,"score_gpt":0.2149553319821013,"score_spread":0.2069251840327345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}