{"id":"W2039018328","doi":"10.1016/j.str.2004.04.018","title":"Pathway Complexity of Alzheimer's β-Amyloid Aβ16-22 Peptide Assembly","year":2004,"lang":"en","type":"article","venue":"Structure","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":130,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Regroupement Québécois sur les Matériaux de Pointe","funders":"","keywords":"Peptide; Amyloid (mycology); P3 peptide; Alzheimer's disease; Chemistry; Amyloid precursor protein; Biochemistry; Neuroscience; Cell biology; Computational biology; Biology; Medicine; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001894835,0.0003536491,0.0003548762,0.0002797999,0.0005936889,0.00117856,0.00034859,0.0004751968,0.001839812],"category_scores_gemma":[0.0004702532,0.000262562,0.0003154306,0.0001977923,0.0001976712,0.001348316,0.0002782221,0.0006357521,0.0005294043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007384408,"about_ca_system_score_gemma":0.0006482991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096342,"about_ca_topic_score_gemma":0.0009970047,"domain_scores_codex":[0.9999003,0.00001379534,0.00000611252,0.00002690866,0.00002202698,0.0000308113],"domain_scores_gemma":[0.9998486,0.00004610789,0.00003035988,0.00001620235,0.00002606977,0.00003254889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009761369,0.0001740085,0.004554425,0.000391961,0.00006808671,0.001099103,0.0002955883,0.02142436,0.9132305,0.0394117,0.001288814,0.01708533],"study_design_scores_gemma":[0.0001142655,0.0006987224,0.02149239,0.00009874396,0.000166661,0.00350303,0.0007288639,0.2066865,0.6227551,0.1271382,0.01650496,0.0001126777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855343,0.001374565,0.008054207,0.0004309123,0.00002249331,0.00003364816,0.0003591989,0.00017552,0.004015181],"genre_scores_gemma":[0.9937676,0.001092157,0.003283181,0.00005686235,0.000009595685,0.00002316941,0.0007613614,0.0000196679,0.0009863095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001839812,"threshold_uncertainty_score":0.006154776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0427600435533114,"score_gpt":0.316617347175627,"score_spread":0.2738573036223156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}