{"id":"W2039037313","doi":"10.1007/s11064-014-1430-z","title":"Thiamine Deficiency: An Update of Pathophysiologic Mechanisms and Future Therapeutic Considerations","year":2014,"lang":"en","type":"review","venue":"Neurochemical Research","topic":"Alcoholism and Thiamine Deficiency","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":false,"ca_institutions":"NeuroRx Research (Canada); Centre Hospitalier de l’Université de Montréal; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Neurology; Thiamine deficiency; Pathophysiology; Thiamine; Neurochemistry; Neuroscience; Medicine; Bioinformatics; Psychology; Biology; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00109257,0.000373743,0.001632755,0.0003420142,0.0001905545,0.00003886138,0.0002773798,0.0005173774,0.0001351946],"category_scores_gemma":[0.0007537526,0.0002437873,0.0002409486,0.0005863767,0.0005133098,0.00005382317,0.0002756714,0.001514076,0.00004563775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003331861,"about_ca_system_score_gemma":0.0004107533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004100611,"about_ca_topic_score_gemma":3.63684e-7,"domain_scores_codex":[0.9964837,0.0006474482,0.0006156073,0.0007989548,0.0008330368,0.0006212289],"domain_scores_gemma":[0.9973592,0.0009618828,0.0001621886,0.0008541223,0.0003613436,0.0003012559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00011399,0.0008300737,0.000002398953,0.03338083,0.00008415222,0.0001856876,0.0001528042,8.461991e-8,0.03715376,0.1124145,0.0008658502,0.8148159],"study_design_scores_gemma":[0.001645077,0.005427513,0.00006384792,0.004122284,0.001569483,0.001409765,0.0001394668,0.0001448744,0.00238366,0.05305375,0.9290322,0.001008084],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001453791,0.9960105,0.00005947931,0.000302974,0.0001119091,0.0009869112,0.00004271496,0.00005052925,0.0009812042],"genre_scores_gemma":[0.01092193,0.9876668,0.0004334954,0.0002250103,0.0003664508,0.00008176989,0.0001812195,0.00005790838,0.0000654199],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9281663,"threshold_uncertainty_score":0.9941359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1501618816422553,"score_gpt":0.4432210616050418,"score_spread":0.2930591799627865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}