{"id":"W2039049126","doi":"10.1016/j.ijpharm.2007.01.004","title":"Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes","year":2007,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"Celator Pharmaceuticals (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Liposome; Triethanolamine; Irinotecan; Chemistry; Copper; Nuclear chemistry; Chromatography; Organic chemistry; Analytical Chemistry (journal); Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005478711,0.00007788862,0.00009670218,0.0001141663,0.0000141182,0.00001163203,0.0003028871,0.00006238068,0.00001698289],"category_scores_gemma":[0.00003875765,0.00006084067,0.00008286608,0.00007249109,0.00004501445,0.000007862164,0.00005761121,0.0001450004,7.340793e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004173085,"about_ca_system_score_gemma":0.00008738098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000143017,"about_ca_topic_score_gemma":0.00005352292,"domain_scores_codex":[0.9991045,0.00002641249,0.0003918791,0.00007477399,0.000289049,0.0001133693],"domain_scores_gemma":[0.9991935,0.00002953512,0.0002867461,0.00008330506,0.0003670053,0.00003992381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003178938,0.00008500624,0.00201949,0.000002553994,0.0001163824,0.000007274336,0.00019907,0.000338016,0.9600453,0.0004227504,0.00001741162,0.03642889],"study_design_scores_gemma":[0.000948255,0.0001293524,0.004611206,0.0000181939,0.00001883967,0.00006954338,0.000182897,0.0001843003,0.9420438,0.0005819933,0.05115033,0.00006124918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950001,0.002258236,0.001072557,0.0004717176,0.000649895,0.0000675814,0.000009211259,0.000001324459,0.0004694033],"genre_scores_gemma":[0.9975666,0.001186691,0.0002679561,0.0004703485,0.0004385283,7.358952e-7,0.000007445846,0.000009881514,0.00005184063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05113292,"threshold_uncertainty_score":0.248101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01699823150554372,"score_gpt":0.3318875969551043,"score_spread":0.3148893654495606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}