{"id":"W2039058558","doi":"10.1016/j.bbrc.2009.10.141","title":"Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils","year":2009,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Unfolded protein response; Cell biology; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004057459,0.0002538929,0.0002233441,0.0004507246,0.0002072049,0.0003827904,0.0003016467,0.0005855977,0.002963429],"category_scores_gemma":[0.0006198171,0.0001981748,0.0002609101,0.0003026007,0.0002516017,0.0004992149,0.000318461,0.000494685,0.0008125788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002075306,"about_ca_system_score_gemma":0.0001476946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003530004,"about_ca_topic_score_gemma":0.0002619659,"domain_scores_codex":[0.9997695,0.00006772304,0.00003446784,0.00002972175,0.00004958779,0.00004898419],"domain_scores_gemma":[0.9997384,0.00005886301,0.00006390292,0.0000577561,0.00005040056,0.00003070734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01138401,0.0004085697,0.09147047,0.0006091216,0.0001730559,0.009004878,0.0005795654,0.0002208255,0.8493909,0.001563389,0.001510864,0.03368443],"study_design_scores_gemma":[0.0007411632,0.003434112,0.4404021,0.000119726,0.000442615,0.06038933,0.001584487,0.001294208,0.460795,0.002555322,0.02819363,0.00004830226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837839,0.009840272,0.002489308,0.0004903406,0.00009891603,0.00006701743,0.0003376135,0.00003750875,0.002855159],"genre_scores_gemma":[0.993928,0.00273451,0.001070608,0.0001158664,0.00006493284,0.00005053927,0.000554763,0.000003882251,0.00147692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002963429,"threshold_uncertainty_score":0.009913623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09265745344606521,"score_gpt":0.3801156632316737,"score_spread":0.2874582097856084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}