{"id":"W2039058578","doi":"10.4161/23723548.2014.969136","title":"p53 isoforms change p53 paradigm","year":2014,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Gene isoform; P53 protein; Biology; Cell fate determination; Suppressor; Cell biology; Cancer; Cancer research; Genetics; Transcription factor; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005433109,0.0004491314,0.0008541908,0.0003040792,0.0001307118,0.0000258912,0.0003043116,0.0006792141,0.0004312962],"category_scores_gemma":[0.0001721489,0.0004299923,0.0004178883,0.0004475884,0.0002350988,0.00007992503,0.000173302,0.0007250385,0.001022988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000496636,"about_ca_system_score_gemma":0.0002877653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001304135,"about_ca_topic_score_gemma":0.00002678422,"domain_scores_codex":[0.9969532,0.0002584117,0.0005503422,0.0007961875,0.0005096832,0.0009321549],"domain_scores_gemma":[0.9979629,0.0000625531,0.0002202806,0.001132829,0.0001166424,0.000504832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003200801,0.0006001047,0.0005205518,0.0001516485,0.0003105033,0.003042779,0.0005575005,0.00005602632,0.9219922,0.009526701,0.001783075,0.06113882],"study_design_scores_gemma":[0.004526359,0.002046006,0.0009129558,0.0000916945,0.0004277532,0.0007146338,0.00004274172,0.001670553,0.3506896,0.001372322,0.6369493,0.000556028],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.814133,0.006390805,0.1066317,0.01007985,0.002142605,0.002299897,0.00001661838,0.0005925029,0.05771301],"genre_scores_gemma":[0.9868555,0.0001434734,0.002731436,0.008246541,0.0006192803,0.0002612765,0.0002076763,0.0001610968,0.0007736955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6351662,"threshold_uncertainty_score":0.9998152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.023138542145072,"score_gpt":0.2763822417188507,"score_spread":0.2532436995737787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}