{"id":"W2039105238","doi":"10.1016/j.bbmt.2006.05.016","title":"Methylenetetrahydrofolate Reductase and Thymidylate Synthase Genotypes and Risk of Acute Graft-versus-Host Disease Following Hematopoietic Cell Transplantation for Chronic Myelogenous Leukemia","year":2006,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; Fred Hutchinson Cancer Research Center","keywords":"Methylenetetrahydrofolate reductase; Odds ratio; Medicine; Internal medicine; Genotype; Gastroenterology; Transplantation; Chronic myelogenous leukemia; Immunology; Hematopoietic stem cell transplantation; Leukemia; Oncology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005772967,0.0002942776,0.000608918,0.0006887807,0.0005376714,0.0005964593,0.0004140901,0.0009217822,0.00127951],"category_scores_gemma":[0.002168825,0.0002767203,0.0004122895,0.0006694315,0.0004039848,0.000464319,0.0003083031,0.001054969,0.0002048221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003027672,"about_ca_system_score_gemma":0.0003648649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001271756,"about_ca_topic_score_gemma":0.001382434,"domain_scores_codex":[0.9996308,0.0001264628,0.00003624333,0.0000495986,0.00005395123,0.0001029038],"domain_scores_gemma":[0.9976641,0.0006756763,0.0006671233,0.0001182942,0.0001258834,0.0007489819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002690542,0.0002157224,0.9921921,0.0000097538,0.0001000793,0.0006888917,0.00005753121,0.0001030609,0.002389057,0.00003862776,0.0000571032,0.00145764],"study_design_scores_gemma":[0.00004822591,0.001136441,0.9944008,0.000006849301,0.0001572738,0.002596178,0.0001724443,0.0004527963,0.0007582242,0.0001171061,0.0001405154,0.00001309487],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99955,0.0001766164,0.00004344367,0.00003492389,0.000006533473,0.000002322299,0.00003455538,0.000001958,0.000149555],"genre_scores_gemma":[0.9996777,0.00007364983,0.00003193955,0.00002117709,0.00001494576,0.00000217438,0.00006263612,0.000001665156,0.0001141292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00127951,"threshold_uncertainty_score":0.004280388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008267246019024278,"score_gpt":0.2568639140847356,"score_spread":0.2485966680657113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}