{"id":"W2039139292","doi":"10.1016/j.beem.2008.01.001","title":"Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate","year":2008,"lang":"en","type":"review","venue":"Best Practice & Research Clinical Endocrinology & Metabolism","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Dihydrotestosterone; LNCaP; Androsterone; Androgen receptor; Androgen; Glucuronidation; Chemistry; Endocrinology; Prostate; Small interfering RNA; Internal medicine; Testosterone (patch); Biology; Prostate cancer; Enzyme; Biochemistry; RNA; Gene; Microsome; Hormone; Medicine; Steroid; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004496617,0.0007270489,0.001220188,0.00148249,0.000123614,0.0006539944,0.0006587458,0.0005924391,0.002092215],"category_scores_gemma":[0.0003473129,0.0002770992,0.0003660478,0.001840676,0.0002910644,0.0005775281,0.0004190225,0.0008587234,0.002014456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004155706,"about_ca_system_score_gemma":0.0008410087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00117599,"about_ca_topic_score_gemma":0.002313758,"domain_scores_codex":[0.9998761,0.00001687162,0.00001596362,0.00002213583,0.00005789339,0.00001090806],"domain_scores_gemma":[0.9998579,0.00005590398,0.00003360823,0.000005087734,0.00003412108,0.00001337594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001008938,0.00004940242,0.000288594,0.005998658,0.0000700377,0.0002872882,0.0000230951,0.0003532752,0.003274667,0.001186041,0.01077912,0.977589],"study_design_scores_gemma":[0.00007931182,0.000204308,0.002583137,0.001922484,0.0002361986,0.003118301,0.00006213815,0.0001856656,0.003314766,0.001677198,0.9865841,0.00003240456],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003230503,0.9984982,0.000197565,0.0001333812,0.00008475589,0.00000395244,0.00002095086,0.000008588424,0.000729572],"genre_scores_gemma":[0.0009421153,0.9980803,0.000173032,0.0000920817,0.00008027229,0.000003326267,0.00003699724,0.000001011128,0.0005909225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002092215,"threshold_uncertainty_score":0.006999135,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5109476191605136,"score_gpt":0.6453303354420363,"score_spread":0.1343827162815228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}