{"id":"W2039205151","doi":"10.1016/j.ijrobp.2012.07.169","title":"Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients with Locally Advanced Non-small Cell Lung Cancer -- An Updated Analysis of RTOG 0214","year":2012,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Prophylactic cranial irradiation; Conventional PCI; Internal medicine; Lung cancer; Radiation therapy; Clinical endpoint; Brain metastasis; Surgery; Cumulative incidence; Proportional hazards model; Oncology; Cancer; Metastasis; Cohort; Randomized controlled trial; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00288205,0.001274486,0.003852403,0.0005821028,0.000308123,0.001325238,0.001070805,0.0008418586,0.002644815],"category_scores_gemma":[0.002159338,0.0004814677,0.003683789,0.000973605,0.0005792378,0.0008378769,0.0004546866,0.001975908,0.0004747434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001383681,"about_ca_system_score_gemma":0.001575617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002235533,"about_ca_topic_score_gemma":0.005362426,"domain_scores_codex":[0.9987726,0.0007482086,0.00006556646,0.0001780212,0.00009767893,0.00013793],"domain_scores_gemma":[0.9986122,0.0005176244,0.0003591753,0.0001619643,0.00009076991,0.0002583236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8945643,0.00542622,0.01692775,0.0007370651,0.007188238,0.00006564581,0.0001398363,0.002595999,0.006381846,0.0001159979,0.001450981,0.06440627],"study_design_scores_gemma":[0.5052822,0.3481663,0.118885,0.0002473541,0.01592309,0.0004277415,0.0002414778,0.00267769,0.002768746,0.0005481444,0.004749801,0.00008255117],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854025,0.009548565,0.0005712823,0.0003196792,0.0001405883,0.0007140222,0.002046629,0.00005390797,0.001202876],"genre_scores_gemma":[0.9887904,0.004265476,0.00086417,0.0005683353,0.0001634929,0.0005784289,0.003529708,0.00006050502,0.00117957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003852403,"threshold_uncertainty_score":0.01524192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02503347235999461,"score_gpt":0.3595473975970352,"score_spread":0.3345139252370407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}