{"id":"W2039229598","doi":"10.1038/sj.mt.6300089","title":"Armed Interference: Oncolytic Viruses Engineered to Carry Antitumor shRNAs","year":2007,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Virology; RNA interference; Interference (communication); Biology; Computational biology; Genetics; Virus; Gene; Computer science; Telecommunications; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004556555,0.0008497665,0.000664242,0.0005075754,0.00011022,0.0001418852,0.001404418,0.001236498,0.0002718493],"category_scores_gemma":[0.00008894939,0.0008379632,0.0004712881,0.0004345673,0.0001625345,0.000004875987,0.0002422891,0.00139629,0.0003219913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001384235,"about_ca_system_score_gemma":0.0004603193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000465595,"about_ca_topic_score_gemma":0.00004574178,"domain_scores_codex":[0.9958255,0.0003125089,0.0005505317,0.001257179,0.0008217447,0.001232588],"domain_scores_gemma":[0.9975055,0.00004005462,0.0001505364,0.001728969,0.0002940849,0.0002808622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00142894,0.00006568433,0.00001703102,0.00003739172,0.0004238197,0.0007045496,0.00005009182,0.00006495341,0.7212873,0.00000171875,0.2708256,0.00509294],"study_design_scores_gemma":[0.0007139197,0.00255519,0.0000129896,0.00004357002,0.00001575253,0.00002460358,0.000007354226,0.000005137062,0.5083193,0.00001682821,0.48772,0.0005654307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.895142,0.01180771,0.00711277,0.07938822,0.00133156,0.002926762,0.0002769277,0.0001907094,0.001823373],"genre_scores_gemma":[0.1034946,0.00113283,0.0006879986,0.8847961,0.003901235,0.000315973,0.001067089,0.0005151766,0.004088969],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8054079,"threshold_uncertainty_score":0.9994071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03176851537991247,"score_gpt":0.3253246079353527,"score_spread":0.2935560925554402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}