{"id":"W2039229598","doi":"10.1038/sj.mt.6300089","title":"Armed Interference: Oncolytic Viruses Engineered to Carry Antitumor shRNAs","year":2007,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Virology; RNA interference; Interference (communication); Biology; Computational biology; Genetics; Virus; Gene; Computer science; Telecommunications; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002183197,0.0005022656,0.000362639,0.0005130016,0.0002140675,0.0005335044,0.0003577034,0.0003373345,0.00270418],"category_scores_gemma":[0.0002391196,0.0002301848,0.000382234,0.0004977299,0.0002200092,0.0003925446,0.0004012597,0.0007889452,0.001400148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004936248,"about_ca_system_score_gemma":0.0003110918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008089739,"about_ca_topic_score_gemma":0.001064768,"domain_scores_codex":[0.9997858,0.00002180574,0.00002211813,0.00003687393,0.0001002865,0.00003306657],"domain_scores_gemma":[0.9999251,0.00001708501,0.00002013704,0.00001305816,0.00001339446,0.00001124265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001538097,0.00004362282,0.000217651,0.0001859403,0.00002935361,0.0001428487,0.0000425352,0.0002857014,0.9715981,0.001837068,0.001968652,0.02349481],"study_design_scores_gemma":[0.00004904636,0.0003233305,0.001205218,0.00002920991,0.00008881978,0.00048515,0.00001814585,0.00207892,0.9181613,0.0005536634,0.0769919,0.0000153912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6711517,0.03228128,0.202046,0.001913739,0.001431661,0.0008300065,0.01384832,0.006383676,0.07011358],"genre_scores_gemma":[0.8561336,0.01490254,0.06729784,0.000667308,0.0001371669,0.0005508828,0.0106892,0.0004991071,0.04912237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00270418,"threshold_uncertainty_score":0.009046376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03176851537991247,"score_gpt":0.3253246079353527,"score_spread":0.2935560925554402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}