{"id":"W2039259357","doi":"10.1002/art.10518","title":"The in situ up‐regulation of chondrocyte interleukin‐1–converting enzyme and interleukin‐18 levels in experimental osteoarthritis is mediated by nitric oxide","year":2002,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Nitric oxide synthase; Chondrocyte; Osteoarthritis; Cartilage; Nitric oxide; Anterior cruciate ligament; Internal medicine; Endocrinology; Chemistry; Interleukin; Medicine; Synovial fluid; Pharmacology; Pathology; Anatomy; Cytokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003129866,0.0003677416,0.0006841146,0.0003414405,0.0001379819,0.00006428587,0.0001484357,0.0001994259,0.0006416398],"category_scores_gemma":[0.0001374292,0.0003424335,0.0001132655,0.0004351112,0.0002313843,0.0004533026,0.0001119992,0.0003174922,0.0000642385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00017559,"about_ca_system_score_gemma":0.0000315974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003367461,"about_ca_topic_score_gemma":0.001075684,"domain_scores_codex":[0.9972363,0.0001466314,0.001108032,0.0005081179,0.0004277287,0.0005732269],"domain_scores_gemma":[0.9988466,0.0002699235,0.0002826372,0.000359702,0.00006467685,0.0001764514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001464392,0.0002779917,0.00720681,0.00004486766,0.00003676025,0.0001090769,0.006195312,4.629999e-7,0.5526117,0.0002654481,0.001102131,0.432003],"study_design_scores_gemma":[0.03310234,0.002535099,0.03559768,0.006582213,0.00003446436,0.000730688,0.003816573,0.0007855797,0.9138969,0.0006600126,0.001530868,0.0007276181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9484419,0.049059,0.00001460081,0.0003092056,0.0002161056,0.000833529,0.00003998491,0.00005938781,0.001026273],"genre_scores_gemma":[0.9938715,0.004780714,0.0002194082,0.000207352,0.00002141455,0.0001502809,0.00006408734,0.00005390315,0.0006314004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4312754,"threshold_uncertainty_score":0.9999028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0167659045302578,"score_gpt":0.2413574756772311,"score_spread":0.2245915711469733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}