{"id":"W2039287501","doi":"10.1006/jmbi.2001.5331","title":"Dimer formation and transcription activation in the sporulation response regulator Spo0A","year":2002,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Phosphorylation; Effector; Transcription (linguistics); Transcription factor; Biology; Response regulator; Cell biology; Mutant; Biochemistry; General transcription factor; Chemistry; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005530664,0.0000869652,0.0001120123,0.0001186097,0.00003148484,0.00001367346,0.0001189915,0.0002477505,0.00000802779],"category_scores_gemma":[0.00009671061,0.00006224706,0.00005404878,0.0000976649,0.00006661902,0.000008661615,0.00001740316,0.0001214629,9.016982e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001174936,"about_ca_system_score_gemma":0.00001058515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002250257,"about_ca_topic_score_gemma":0.000003489038,"domain_scores_codex":[0.9991531,0.0002591725,0.000291264,0.0001103218,0.00006840838,0.0001177398],"domain_scores_gemma":[0.9995669,0.00001397076,0.0001953654,0.0001362097,0.00006532117,0.0000222655],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003564477,0.00003278764,0.0002433114,0.000003267111,0.00001246871,0.000002640511,0.00009354857,0.0000139013,0.9927865,0.000207656,0.00009091916,0.006156527],"study_design_scores_gemma":[0.001091894,0.00127991,0.01939807,0.0000166747,0.00002226285,0.0002697973,0.0001104691,0.0001406105,0.9554614,0.0008837594,0.02119288,0.0001322004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915521,0.0006301764,0.004944762,0.002640417,0.00009343764,0.0001067499,0.000001651244,0.00000193929,0.00002872969],"genre_scores_gemma":[0.9986551,0.0002757689,0.0005899338,0.0003583482,0.00008528793,0.000002528603,0.00001380371,0.000006646427,0.00001260874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03732505,"threshold_uncertainty_score":0.2538361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0105523154076761,"score_gpt":0.2344878336117049,"score_spread":0.2239355182040288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}