{"id":"W2039312410","doi":"10.1210/jc.2004-0318","title":"Differential Role of Progesterone Receptor Isoforms in the Transcriptional Regulation of Human Gonadotropin-Releasing Hormone I (GnRH I) Receptor, GnRH I, and GnRH II","year":2005,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gonadotropin-releasing hormone; Transfection; Receptor; Internal medicine; Endocrinology; Luciferase; Progesterone receptor; Biology; Gene isoform; Gonadotropin-releasing hormone receptor; Transcriptional regulation; Activator (genetics); Cell culture; Hormone; Chemistry; Luteinizing hormone; Transcription factor; Gene; Estrogen receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000128155,0.0001319,0.0001799772,0.0002285006,0.0001056581,0.0003551717,0.0001080763,0.0001510336,0.0007069036],"category_scores_gemma":[0.0002244615,0.0001629086,0.0002866578,0.0001337944,0.0001878975,0.0002105522,0.0001311174,0.0002193059,0.0002624907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001918616,"about_ca_system_score_gemma":0.0002382437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001023376,"about_ca_topic_score_gemma":0.0009462977,"domain_scores_codex":[0.9998492,0.00002569836,0.00001571027,0.00004289655,0.00002931977,0.0000371498],"domain_scores_gemma":[0.9999019,0.0000195595,0.00002774089,0.00001134145,0.00001749479,0.00002188059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003584454,0.00001659801,0.00260236,0.00003572487,0.0000101158,0.0001813086,0.00006968803,0.00003473832,0.9941765,0.0001279479,0.00005494187,0.002331604],"study_design_scores_gemma":[0.00009964701,0.0009230229,0.17539,0.00002622025,0.00009212082,0.002362419,0.0006717572,0.001377382,0.810958,0.0002778828,0.00779798,0.00002357156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937481,0.002872342,0.001345904,0.0001367069,0.00003308857,0.00002255967,0.0003382589,0.00002910148,0.001473877],"genre_scores_gemma":[0.9932301,0.002149629,0.0011423,0.00008934095,0.00001817348,0.00002517796,0.0004379967,0.00001257659,0.002894745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001023376,"threshold_uncertainty_score":0.002364874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03192008427870664,"score_gpt":0.3306421005478717,"score_spread":0.2987220162691651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}