{"id":"W2039312410","doi":"10.1210/jc.2004-0318","title":"Differential Role of Progesterone Receptor Isoforms in the Transcriptional Regulation of Human Gonadotropin-Releasing Hormone I (GnRH I) Receptor, GnRH I, and GnRH II","year":2005,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Gonadotropin-releasing hormone; Transfection; Receptor; Internal medicine; Endocrinology; Luciferase; Progesterone receptor; Biology; Gene isoform; Gonadotropin-releasing hormone receptor; Transcriptional regulation; Activator (genetics); Cell culture; Hormone; Chemistry; Luteinizing hormone; Transcription factor; Gene; Estrogen receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001579106,0.0002617337,0.001455935,0.0002452657,0.0001309824,0.000008664196,0.0004065757,0.0001896933,0.0001349149],"category_scores_gemma":[0.0006829292,0.0001466767,0.0003902799,0.0001822089,0.0009533961,0.0002507902,0.00008214657,0.001137049,0.000003729207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003252787,"about_ca_system_score_gemma":0.0001336562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003787648,"about_ca_topic_score_gemma":0.00001355488,"domain_scores_codex":[0.9953013,0.0008953952,0.002486639,0.0002719663,0.0006534617,0.0003912361],"domain_scores_gemma":[0.9969698,0.000546813,0.001475914,0.0004760305,0.0004244035,0.0001070425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004426976,0.001269055,0.008842668,0.00002998934,0.000484855,0.000003367113,0.001955459,0.00001694394,0.8805232,0.00439082,0.0001911706,0.0978655],"study_design_scores_gemma":[0.008730685,0.001678828,0.961966,0.0000921036,0.0007255456,0.0004199786,0.0005212476,0.0000494204,0.01143718,0.00155913,0.01268705,0.0001328366],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726877,0.01369682,0.0001177738,0.01255195,0.0003137876,0.0005166442,0.000009784234,0.00001034252,0.0000951706],"genre_scores_gemma":[0.9926823,0.004005342,0.001178875,0.0001945236,0.001765438,0.000007354743,0.000008197473,0.00002557074,0.0001323425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9531233,"threshold_uncertainty_score":0.59813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03192008427870664,"score_gpt":0.3306421005478717,"score_spread":0.2987220162691651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}