{"id":"W2039313393","doi":"10.1016/j.neurobiolaging.2004.06.012","title":"Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system","year":2004,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Alzheimer Society","keywords":"Microglia; THP1 cell line; Endogeny; Neuroscience; Central nervous system; Toxicity; Immunology; Human cell; Cell biology; Biology; Cell culture; Medicine; Inflammation; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001221989,0.0001288619,0.0001837738,0.0000888435,0.000207015,0.00001623056,0.000209859,0.00004373614,0.000003764003],"category_scores_gemma":[0.00003826514,0.0001021662,0.00003997477,0.0001580098,0.00009056758,0.00006359834,0.00008189479,0.00009742208,0.000006386264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001223815,"about_ca_system_score_gemma":0.00001392026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002348408,"about_ca_topic_score_gemma":0.000008081055,"domain_scores_codex":[0.9988772,0.000195386,0.0003242802,0.0003335652,0.0001012514,0.0001682677],"domain_scores_gemma":[0.9993732,0.00008855551,0.000209484,0.0002448953,0.00003949868,0.00004438258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007282168,0.00002565677,0.00005886388,0.00003438832,8.738324e-7,0.000002447248,0.0002506376,0.002033248,0.9956248,0.001833967,0.00005816733,0.00006969756],"study_design_scores_gemma":[0.0002869514,0.0002154056,0.0004459884,0.00001155024,0.000006632471,0.00005131358,0.00002469203,0.0001203353,0.9986188,0.0000698005,0.00007286552,0.00007563242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978037,0.00001478299,0.0006638721,0.0005754012,0.0003537382,0.0003118637,0.00002960115,0.00006044463,0.0001865342],"genre_scores_gemma":[0.9990036,0.00001190169,0.00009708313,0.0007601026,0.00005395773,0.000007010393,0.000003264404,0.00001457317,0.00004851446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002994062,"threshold_uncertainty_score":0.4166218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02669860121753023,"score_gpt":0.232951671859865,"score_spread":0.2062530706423347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}