{"id":"W2039371098","doi":"10.3109/10606820308244","title":"Activity, Regulation, and Intracellular Localization of RGS Proteins","year":2003,"lang":"en","type":"article","venue":"Receptors and Channels","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Heterotrimeric G protein; G protein; GTPase-activating protein; Cell biology; RGS2; Intracellular; GTP'; Chemistry; GTP-binding protein regulators; Biology; Biochemistry; Signal transduction; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553618,0.00008454851,0.00009498005,0.00003387496,0.00006354087,0.00001330401,0.00002230376,0.00009979107,0.00003114975],"category_scores_gemma":[0.00004549967,0.00008089283,0.00002209927,0.00006743451,0.00006484936,0.000005716682,0.000021111,0.00002858021,5.175308e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003814403,"about_ca_system_score_gemma":0.00001870937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007175708,"about_ca_topic_score_gemma":0.000001951469,"domain_scores_codex":[0.9994933,0.00005487674,0.0001120363,0.000175425,0.00007185088,0.00009253157],"domain_scores_gemma":[0.999719,0.000003669421,0.00007243576,0.00009473608,0.0000570102,0.00005312236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003153581,0.00004293535,0.001137364,0.00007012085,0.00002060695,2.752276e-7,0.0001054878,0.0003509408,0.9867152,0.001939814,0.0001466043,0.009439101],"study_design_scores_gemma":[0.0002834222,0.0001078582,0.0001811729,0.00002614683,0.000007685865,0.000006141748,0.00003245701,0.0008301139,0.9775603,0.0007604092,0.02009693,0.0001072945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9150596,0.001548401,0.08277749,0.00005781944,0.0000848594,0.000256737,0.000002824218,0.000007483901,0.0002047606],"genre_scores_gemma":[0.9988195,0.0002262775,0.0004655006,0.00001999844,0.00007794626,0.00001093759,0.0000192038,0.00001015479,0.0003504568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0837599,"threshold_uncertainty_score":0.3298714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008923077439299185,"score_gpt":0.2210464948552366,"score_spread":0.2121234174159374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}