{"id":"W2039394771","doi":"10.1038/ja.2013.100","title":"Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics","year":2013,"lang":"en","type":"review","venue":"The Journal of Antibiotics","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Teichoic acid; Peptidoglycan; Cell wall; Biogenesis; Bacterial cell structure; Biology; Bacteria; Gram-positive bacteria; Microbiology; Biochemistry; Cell division; Function (biology); Cell envelope; Antibiotics; Cell; Cell biology; Gene; Genetics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005156649,0.0009514033,0.001377098,0.001557848,0.0002834169,0.001164891,0.0008264359,0.001134432,0.003494728],"category_scores_gemma":[0.0005313641,0.0003386127,0.000443652,0.001951305,0.0006714883,0.001891363,0.0008934375,0.002197894,0.002464838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000596097,"about_ca_system_score_gemma":0.0008323205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000532066,"about_ca_topic_score_gemma":0.0012918,"domain_scores_codex":[0.9998079,0.00002554977,0.00002367335,0.00003408923,0.00007740688,0.00003145926],"domain_scores_gemma":[0.999745,0.00009917471,0.00004122276,0.000009943851,0.00006977799,0.00003495988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001423562,0.0001057404,0.0001253145,0.01326214,0.00008391128,0.0002811238,0.00006220409,0.0004757045,0.008144013,0.006284266,0.04082818,0.9302051],"study_design_scores_gemma":[0.00002509477,0.0001103605,0.000281733,0.0009964944,0.0000599153,0.0007216293,0.00004046528,0.0001092164,0.001271349,0.002062881,0.9943004,0.00002049812],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002061876,0.9977962,0.0002577615,0.0003564268,0.00038042,0.000003955557,0.00001876708,0.00001114166,0.0009692687],"genre_scores_gemma":[0.001140921,0.9972131,0.000286554,0.0002333868,0.000291714,0.00000399925,0.00002707046,0.000002007182,0.0008012705],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003494728,"threshold_uncertainty_score":0.01169109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08784225639130676,"score_gpt":0.3521559601371118,"score_spread":0.264313703745805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}