{"id":"W2039395591","doi":"10.3791/51253","title":"A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies","year":2014,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Cancer Society Research Institute; University of Ottawa","keywords":"Medicine; Surgical stress; Perioperative; Breast cancer; Immune system; Immunotherapy; Cancer; Immunosuppression; Lung cancer; Primary tumor; Metastasis; Oncology; Surgery; Pathology; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005789831,0.001469267,0.0008356738,0.001518829,0.000499422,0.0007158468,0.0006857423,0.001487797,0.004380874],"category_scores_gemma":[0.0002014487,0.0004665137,0.0009450814,0.0007243172,0.0006207316,0.0008673865,0.0004641438,0.003845714,0.001360939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005237592,"about_ca_system_score_gemma":0.000674002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007822373,"about_ca_topic_score_gemma":0.001241909,"domain_scores_codex":[0.9994612,0.00006076763,0.00006336889,0.0001276897,0.0001502226,0.0001367126],"domain_scores_gemma":[0.9995366,0.0000547799,0.0001422021,0.00007292401,0.00005094219,0.0001424861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001111142,0.001233107,0.0006423524,0.0002551084,0.00003686284,0.0002405309,0.00009004113,0.0005087501,0.9893633,0.001090609,0.000774881,0.004653339],"study_design_scores_gemma":[0.0003548433,0.01138052,0.005648467,0.000159634,0.0002068156,0.001315742,0.0002289569,0.004248062,0.9500467,0.0008466186,0.02550218,0.00006148737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9313614,0.00942775,0.03669165,0.001790654,0.001361854,0.0009750669,0.008304604,0.001167444,0.008919694],"genre_scores_gemma":[0.9078225,0.01031678,0.03851955,0.0009539577,0.000192539,0.002836369,0.008236411,0.0002979558,0.03082393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004380874,"threshold_uncertainty_score":0.01465553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04771908520371848,"score_gpt":0.406543422252766,"score_spread":0.3588243370490475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}