{"id":"W2039404107","doi":"10.1080/15257770601112762","title":"Synthesis of 3’,5’-cyclic diguanylic acid (cdiGMP) Using 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl as a Protecting Group for 2’-hydroxy Functions of Ribonucleosides","year":2007,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Protecting group; Context (archaeology); Guanine; Stereochemistry; Phosphonate; Chemistry; Nucleoside; Group (periodic table); Oligonucleotide; Yield (engineering); Homogeneous; Nucleotide; Biology; Mathematics; Biochemistry; Combinatorics; Organic chemistry; DNA; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001719945,0.0009360028,0.001243503,0.0003737166,0.0006736734,0.00009415168,0.001103407,0.0008111232,0.0001876946],"category_scores_gemma":[0.002168604,0.0009857382,0.001038883,0.0007002224,0.001012238,0.0000962022,0.0005321373,0.0005028315,0.00002374251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001431753,"about_ca_system_score_gemma":0.0001780298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002010783,"about_ca_topic_score_gemma":0.00005192314,"domain_scores_codex":[0.9945073,0.000156134,0.001879535,0.001387213,0.0006895387,0.001380328],"domain_scores_gemma":[0.9957524,0.0004051244,0.001251759,0.001556645,0.0005667009,0.0004673847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001211953,0.0004879003,0.004460035,0.0005685513,0.0004604331,0.0000112444,0.0003112744,0.00008255357,0.9797695,0.0003715781,0.0003404805,0.01192446],"study_design_scores_gemma":[0.001393475,0.0009881301,0.002549518,0.0003967555,0.0004211335,0.0001531665,0.002145158,0.0004242206,0.9808896,0.0005106666,0.009121936,0.001006283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872323,0.0007125956,0.006592014,0.00009675702,0.0004611656,0.001198116,0.0002012706,0.0001668308,0.003338905],"genre_scores_gemma":[0.975716,0.0001114031,0.02256354,0.0002006963,0.0006810441,0.00009922763,0.00007175822,0.0003537459,0.0002025911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01597152,"threshold_uncertainty_score":0.9992593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320543854827236,"score_gpt":0.262426435730334,"score_spread":0.2492209971820616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}