{"id":"W2039407113","doi":"10.1074/jbc.m211278200","title":"Calcium/Calmodulin-dependent Protein Kinase II Regulation of c-FLIP Expression and Phosphorylation in Modulation of Fas-mediated Signaling in Malignant Glioma Cells","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Fas ligand; Apoptosis; Phosphorylation; Signal transduction; Flip; Fas receptor; FADD; Biology; Cell biology; Caspase 8; Molecular biology; Cancer research; Chemistry; Programmed cell death; Caspase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005752211,0.0001269474,0.0002566889,0.00006428856,0.00002361759,0.000004621939,0.0000710415,0.0003434882,0.00003075417],"category_scores_gemma":[0.0001659408,0.00009781679,0.00007240473,0.0001207314,0.00005195742,0.000008776591,0.00003934432,0.0001179643,7.40206e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003182749,"about_ca_system_score_gemma":0.00004042547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006696121,"about_ca_topic_score_gemma":0.000001114822,"domain_scores_codex":[0.9987092,0.00009226855,0.0006974172,0.0001978576,0.0001739822,0.0001292768],"domain_scores_gemma":[0.9991026,0.00002123844,0.0005743612,0.0001120075,0.0001340492,0.00005576171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002768746,0.000172113,0.002480994,0.00004771911,0.000007210495,0.000006114968,0.00003667538,0.004797113,0.9916174,0.00001316409,0.000001859008,0.0005427441],"study_design_scores_gemma":[0.001057207,0.0002836786,0.009324679,0.0001646055,0.000005579944,0.00001341659,0.00007606958,0.001166684,0.9874666,0.0003092152,0.0000263764,0.0001058445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973561,0.000700057,0.001691595,0.00001143891,0.00003519245,0.0001600253,0.000004668492,0.000001696295,0.00003929701],"genre_scores_gemma":[0.9979462,0.00008254772,0.001846803,0.000003120899,0.00004124585,0.000003686003,0.00003362384,0.000007224768,0.00003551696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006843685,"threshold_uncertainty_score":0.3988853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01394550168226839,"score_gpt":0.2290584608258757,"score_spread":0.2151129591436073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}