{"id":"W2039444662","doi":"10.1016/s0002-9440(10)64246-0","title":"Correlation of DNA Hypomethylation at Pericentromeric Heterochromatin Regions of Chromosomes 16 and 1 with Histological Features and Chromosomal Abnormalities of Human Breast Carcinomas","year":2002,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Medical Research Council; McGill University; Ministry of Health, Labour and Welfare; Case Western Reserve University","keywords":"Biology; Heterochromatin; Chromosome; Cytogenetics; DNA; DNA methylation; Genetics; Pathology; Chromatin; Gene; Medicine; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001450893,0.0001208528,0.0004115507,0.0001188488,0.00004914305,0.000003181062,0.00007062506,0.00007986354,0.00001815798],"category_scores_gemma":[0.00004401767,0.00009655032,0.00006261194,0.0001083258,0.0008916799,0.000009926552,0.00004641647,0.00007714648,7.24555e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001894228,"about_ca_system_score_gemma":0.00001676614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000271451,"about_ca_topic_score_gemma":0.00001599892,"domain_scores_codex":[0.9989754,0.0001848576,0.0004393248,0.000146601,0.0001326611,0.000121163],"domain_scores_gemma":[0.9984877,0.00005080915,0.001093017,0.0001305831,0.0001787664,0.00005919149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001446436,0.00008099957,0.09904483,0.00003956915,0.00005797419,0.00001244426,0.0007695718,0.00006108219,0.8960668,0.00009130561,0.00001613046,0.003614577],"study_design_scores_gemma":[0.001143878,0.008793883,0.8568896,0.00005376779,0.0001320047,0.002798384,0.0007974925,0.00005834677,0.1289993,0.0001030878,0.00005359971,0.0001766479],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942554,0.004747895,0.0006629705,0.0000582727,0.00002607815,0.00006519374,0.00001908521,0.000001578753,0.0001635163],"genre_scores_gemma":[0.997936,0.0006782631,0.00126603,0.00001021588,0.00004118964,0.000001517878,0.0000162644,0.00001009583,0.00004039738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7670676,"threshold_uncertainty_score":0.3937208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009177248709676268,"score_gpt":0.2227432302179994,"score_spread":0.2135659815083231,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}