{"id":"W2039483745","doi":"10.3390/md13031202","title":"Anticancer Activity of Sea Cucumber Triterpene Glycosides","year":2015,"lang":"en","type":"review","venue":"Marine Drugs","topic":"Echinoderm biology and ecology","field":"Agricultural and Biological Sciences","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Public Health Agency of Canada","keywords":"Triterpene; Protein kinase B; Biology; Cell growth; MAPK/ERK pathway; Cell cycle checkpoint; Kinase; Biochemistry; Signal transduction; Cell biology; Chemistry; Cell cycle; Apoptosis; Pharmacology; Medicine; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004106658,0.0002818515,0.00135066,0.00002004807,0.00006531368,0.00001208979,0.0003759406,0.0004603387,0.0016809],"category_scores_gemma":[0.00005523563,0.00009681533,0.0002798036,0.0002838177,0.0001340593,0.00005862828,0.0004141973,0.0003118476,0.0001149412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004148343,"about_ca_system_score_gemma":0.00004658218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00296234,"about_ca_topic_score_gemma":0.004600246,"domain_scores_codex":[0.9985937,0.0002569275,0.0003445863,0.0003758788,0.0001190752,0.0003097687],"domain_scores_gemma":[0.9990593,0.0003708471,0.0003135371,0.0001084505,0.00005697786,0.00009091302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001818931,0.00008009582,0.002153979,0.0005882639,0.0000538726,0.000005431131,0.00000799487,2.390568e-8,0.00001689787,0.00002596209,0.001213084,0.9958362],"study_design_scores_gemma":[0.00008421088,0.000149882,0.00065776,0.0002571559,0.0001614927,0.00002433387,0.00000545479,0.000005422984,0.00002273632,0.0002424009,0.998154,0.0002351139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03343173,0.9538747,1.553233e-7,0.0001596258,0.0003596174,0.0004344584,0.000186442,0.00005492679,0.01149831],"genre_scores_gemma":[0.003770832,0.9939142,0.00002968852,0.00005911812,0.0002946316,0.00004126126,0.0003305345,0.000002142157,0.001557634],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.996941,"threshold_uncertainty_score":0.9992317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05072636335009138,"score_gpt":0.3096744001255811,"score_spread":0.2589480367754897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}