{"id":"W2039516909","doi":"10.1117/12.701086","title":"Two-photon photodynamic therapy and its potential application to age related macular degenerations","year":2007,"lang":"en","type":"article","venue":"Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Princess Margaret Cancer Centre; University of Waterloo; University of Toronto","funders":"","keywords":"Verteporfin; Photodynamic therapy; Macular degeneration; Choroidal neovascularization; In vivo; Materials science; Two-photon excitation microscopy; Medicine; Biomedical engineering; Chemistry; Ophthalmology; Optics; Physics; Fluorescence; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634369,0.0002717706,0.0002151705,0.0004591194,0.0001487725,0.0002997198,0.0001861377,0.00084675,0.001671074],"category_scores_gemma":[0.0001266182,0.0001131692,0.0002195875,0.0002783556,0.0002782582,0.0002648919,0.000210838,0.0003325681,0.0001755469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002677617,"about_ca_system_score_gemma":0.0001779125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003628947,"about_ca_topic_score_gemma":0.0003866752,"domain_scores_codex":[0.9999006,0.00003546393,0.000002277842,0.00001572164,0.00002442541,0.00002149587],"domain_scores_gemma":[0.999945,0.00002753661,0.000006883805,0.000003520359,0.000006889427,0.00001004268],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003718573,0.0002228901,0.00115117,0.0006614895,0.00001948537,0.0008492275,0.0001037635,0.001824278,0.918811,0.004482045,0.0007142097,0.07078863],"study_design_scores_gemma":[0.0001053089,0.003151155,0.01876555,0.0002213838,0.00006843483,0.009313806,0.0001454365,0.008640289,0.8531317,0.005950146,0.1004443,0.00006261413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5671892,0.3732223,0.03668021,0.002417114,0.0002746308,0.00009634511,0.0001540786,0.0002537463,0.01971238],"genre_scores_gemma":[0.8855818,0.09297869,0.01296118,0.0004805019,0.0001390025,0.00004728645,0.0001092032,0.00001291333,0.007689394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001671074,"threshold_uncertainty_score":0.00559032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01112671054013256,"score_gpt":0.271269225653534,"score_spread":0.2601425151134014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}