{"id":"W2039533616","doi":"10.3389/fgene.2014.00419","title":"Phospholipase A2 â€“ nexus of aging, oxidative stress, neuronal excitability, and functional decline of the aging nervous system? Insights from a snail model system of neuronal aging and age-associated memory impairment","year":2014,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"Medicinal Plants and Neuroprotection","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuroscience; Context (archaeology); Lymnaea stagnalis; Brain aging; Aging brain; Neurodegeneration; Oxidative stress; Cognitive decline; Biology; Disease; Memory impairment; Ageing; Psychology; Cognition; Snail; Medicine; Dementia; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000247641,0.0005420411,0.0007605666,0.001228007,0.0002070981,0.0007032298,0.0003656642,0.0007663399,0.001524258],"category_scores_gemma":[0.000214816,0.0001829181,0.0002663354,0.001549876,0.0003961656,0.001268309,0.0004609219,0.001079444,0.0009917147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003981189,"about_ca_system_score_gemma":0.0005992373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006459198,"about_ca_topic_score_gemma":0.001036789,"domain_scores_codex":[0.9999382,0.000009624745,0.00001084412,0.00001366549,0.00002090791,0.000006807065],"domain_scores_gemma":[0.9999346,0.00001957585,0.0000145747,0.000002505035,0.00001930966,0.000009494951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001409026,0.00009272459,0.0003470479,0.01690838,0.00009980624,0.0003610152,0.0001104015,0.0004816215,0.01251928,0.009095512,0.02738987,0.9324533],"study_design_scores_gemma":[0.0000191669,0.0001476947,0.001864569,0.002007078,0.00008396695,0.001771892,0.0001224664,0.0002133611,0.001662707,0.004024572,0.9880574,0.00002518005],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003097785,0.9980447,0.0001975504,0.0004463742,0.0001881677,0.000002872114,0.00001422194,0.000006023302,0.0007903544],"genre_scores_gemma":[0.001531596,0.9970257,0.0002179962,0.0001947475,0.0002468744,0.000004818622,0.00001942125,0.000001003716,0.0007578516],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001524258,"threshold_uncertainty_score":0.005099177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02495949292859223,"score_gpt":0.2564217690344452,"score_spread":0.231462276105853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}