{"id":"W2039587320","doi":"10.1002/dvdy.20658","title":"Complementary Gli activity mediates early patterning of the mouse visual system","year":2005,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Cancer Institute; Canadian Institutes of Health Research; CNIB; Baker Foundation","keywords":"GLI3; GLI2; Biology; Eye development; GLI1; Sonic hedgehog; Hedgehog signaling pathway; Hedgehog; Repressor; Homeobox; Transcription factor; In situ hybridization; Cell biology; Genetics; Signal transduction; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001352914,0.0001478142,0.0001433038,0.00002469716,0.0001338442,0.00001088521,0.0002153007,0.00006251258,0.000006496149],"category_scores_gemma":[0.00001705809,0.0001203814,0.00006572174,0.00006715403,0.00008525029,0.000004734827,0.0003451405,0.00007860743,0.000006730949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001394549,"about_ca_system_score_gemma":0.00006098305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007006367,"about_ca_topic_score_gemma":0.0004520006,"domain_scores_codex":[0.9991361,0.00005352903,0.000214022,0.0002115465,0.0001809425,0.0002038795],"domain_scores_gemma":[0.9996623,0.00001311626,0.0001117824,0.0001307072,0.00004393141,0.00003813531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005561108,0.0001187597,0.2366586,0.00009123276,0.0002480202,0.000002377216,0.0006343371,0.0002222697,0.7534097,0.00008161506,0.0001789019,0.008298612],"study_design_scores_gemma":[0.0006016282,0.00009432183,0.1155046,0.00004929088,0.00002263883,0.00001444804,0.0009761886,0.003586758,0.8778628,0.00000275306,0.0009750974,0.0003094488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981426,0.00004272403,0.001111375,0.00007475906,0.0001140006,0.0001545617,0.0001114468,0.00001760483,0.0002309029],"genre_scores_gemma":[0.9979929,0.000007031088,0.001577716,0.00008413901,0.00007652551,0.00001246147,0.0001069695,0.00002030476,0.000121941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1244531,"threshold_uncertainty_score":0.4909013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009494435552316643,"score_gpt":0.233591566372761,"score_spread":0.2240971308204443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}