{"id":"W2039650836","doi":"10.1023/b:nere.0000035803.64724.17","title":"Local Perfusion of Nicotine Differentially Modulates Somatodendritic Dopamine Release in the Rat Ventral Tegmental Area After Nicotine Preexposure","year":2004,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"Ventral tegmental area; Nicotine; Microdialysis; Mecamylamine; Nicotinic agonist; Chemistry; Nicotinic Antagonist; Dopamine; Pharmacology; Antagonist; Acetylcholine; Extracellular; Endocrinology; Internal medicine; Medicine; Dopaminergic; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001149348,0.0003879686,0.0006268029,0.000215728,0.0002473286,0.0004967431,0.0004159745,0.0004173088,0.001873159],"category_scores_gemma":[0.0002534711,0.0002469222,0.0003903304,0.0001973097,0.0006358351,0.0006409486,0.000237866,0.001118061,0.0003021274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006707416,"about_ca_system_score_gemma":0.0005778986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002979987,"about_ca_topic_score_gemma":0.008634409,"domain_scores_codex":[0.99988,0.000008291629,0.000006019084,0.00002531528,0.0000213311,0.00005913164],"domain_scores_gemma":[0.9998306,0.00003606952,0.00002796252,0.00001714313,0.00002617987,0.00006193346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001704388,0.00007976469,0.0002491295,0.00003826542,0.00001085098,0.00008445141,0.00004232325,0.0000379309,0.9962575,0.00008299627,0.00003198757,0.001380502],"study_design_scores_gemma":[0.00007593323,0.001551838,0.01423896,0.00001365465,0.0000866706,0.0001359089,0.000158681,0.001048972,0.9821583,0.0001037105,0.0004152317,0.00001204391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974382,0.0006531033,0.0007102666,0.00007535349,0.00006358243,0.00002103389,0.000127404,0.00002934983,0.000881673],"genre_scores_gemma":[0.9949651,0.0008196759,0.0006660404,0.00005168174,0.00003341514,0.00006156604,0.000183399,0.00002358912,0.003195441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002979987,"threshold_uncertainty_score":0.006266356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01819004235698142,"score_gpt":0.2995440624110973,"score_spread":0.2813540200541159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}