{"id":"W2039655891","doi":"10.1159/000054703","title":"Effect of Long-Term Treatment with the Antiestrogen EM-652.HCl on Pituitary Estrogen Receptor Alpha and Prolactin mRNA Expression in Intact, Ovariectomized and Gonadotropin- Releasing Hormone-Treated Female Rats","year":2001,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Endocrinology; Internal medicine; Prolactin; Ovariectomized rat; Estrogen; Antiestrogen; Estrogen receptor; Agonist; Estrogen receptor alpha; Anterior pituitary; Prolactin cell; Hormone; Biology; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001347026,0.000409617,0.0003728358,0.0002704696,0.0001632564,0.0002178971,0.0001969704,0.0003230833,0.001085909],"category_scores_gemma":[0.0001481251,0.0002304026,0.0003037847,0.0001481218,0.0002730161,0.0002409443,0.0001540058,0.0005862578,0.0002736186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002219945,"about_ca_system_score_gemma":0.0002496482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008679057,"about_ca_topic_score_gemma":0.002721207,"domain_scores_codex":[0.9998822,0.00002173255,0.00001121597,0.00002400014,0.00002188853,0.00003885749],"domain_scores_gemma":[0.9997756,0.00003409554,0.00005517473,0.00002101623,0.0000231306,0.00009106392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004458721,0.0003117444,0.0008046184,0.00003804396,0.00003435779,0.00009000029,0.00002630771,0.00004955672,0.9915739,0.00002542965,0.00005544149,0.002531844],"study_design_scores_gemma":[0.0002845979,0.01635186,0.02820006,0.00001515318,0.0001745108,0.0003907497,0.0001592589,0.0005057063,0.9506828,0.00004395323,0.00316477,0.00002671095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974735,0.001532816,0.0002233432,0.00007167005,0.00003225589,0.00000986354,0.0002523221,0.0000244401,0.0003798396],"genre_scores_gemma":[0.9930009,0.001483548,0.0006403082,0.0001274065,0.00003933982,0.00003314157,0.0009573289,0.00001690652,0.003701207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085909,"threshold_uncertainty_score":0.003632724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005867135826841737,"score_gpt":0.2411622682217111,"score_spread":0.2352951323948693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}