{"id":"W2039655891","doi":"10.1159/000054703","title":"Effect of Long-Term Treatment with the Antiestrogen EM-652.HCl on Pituitary Estrogen Receptor Alpha and Prolactin mRNA Expression in Intact, Ovariectomized and Gonadotropin- Releasing Hormone-Treated Female Rats","year":2001,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Endocrinology; Internal medicine; Prolactin; Ovariectomized rat; Estrogen; Antiestrogen; Estrogen receptor; Agonist; Estrogen receptor alpha; Anterior pituitary; Prolactin cell; Hormone; Biology; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003156344,0.0003751873,0.0004450682,0.0001136502,0.0001262502,0.00002317655,0.000134375,0.0001421071,0.000003804719],"category_scores_gemma":[0.00003490198,0.0002295283,0.00007588272,0.0001289678,0.0002249057,0.00001177003,0.0001100651,0.0002669179,0.000002623351],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000323776,"about_ca_system_score_gemma":0.00003869739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004264282,"about_ca_topic_score_gemma":0.0000131944,"domain_scores_codex":[0.9980417,0.0005596299,0.0002531596,0.0005777635,0.000111294,0.0004564105],"domain_scores_gemma":[0.9992034,0.0001299425,0.0001583544,0.0003782047,0.00002914433,0.0001008947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01584154,0.0001659098,0.1554504,0.00003206563,0.0001616555,0.0004931539,0.00006700239,0.000009990941,0.8092638,0.00000589369,0.00003620445,0.01847238],"study_design_scores_gemma":[0.006752689,0.01647314,0.08237392,0.00006407847,0.0001304113,0.001149474,0.00003149752,0.00001944462,0.892458,0.000001382305,0.0003217592,0.0002242295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923494,0.006395118,0.000005762393,0.0001823128,0.00005972373,0.0009172747,0.000007803782,0.00002621344,0.0000564021],"genre_scores_gemma":[0.9884522,0.01110627,0.00005389753,0.00005751156,0.00005615494,0.00009280867,0.00005708041,0.00004477796,0.00007927382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0831942,"threshold_uncertainty_score":0.9359891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005867135826841737,"score_gpt":0.2411622682217111,"score_spread":0.2352951323948693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}