{"id":"W2039687494","doi":"10.1038/mt.2009.283","title":"Intelligent Design: Combination Therapy With Oncolytic Viruses","year":2009,"lang":"en","type":"review","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Toronto General Hospital; McMaster University; University of Toronto","funders":"","keywords":"Oncolytic virus; Virotherapy; Radiation therapy; Medicine; Disease; Modalities; Clinical trial; Combination therapy; Cancer; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006673618,0.0009432018,0.001236928,0.000300316,0.0001506289,0.0001436032,0.001001338,0.0006346073,0.00009657117],"category_scores_gemma":[0.00002500252,0.0007070504,0.0006256328,0.0005288728,0.0001725133,0.000006882456,0.0000685318,0.0004785829,0.0001215708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001367317,"about_ca_system_score_gemma":0.0008701744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007707862,"about_ca_topic_score_gemma":0.000008658429,"domain_scores_codex":[0.9958983,0.001085759,0.0005997767,0.001069101,0.000656417,0.0006906528],"domain_scores_gemma":[0.9977444,0.00005411278,0.0003528473,0.001421149,0.000219549,0.0002079737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001797256,0.000474491,6.386497e-7,0.0001882203,0.0007974366,0.00006256596,0.00002288272,0.00004910045,0.0108749,0.00003003275,0.000308955,0.9853935],"study_design_scores_gemma":[0.001381612,0.01507155,6.325584e-7,0.0007087578,0.00007566623,0.00005316353,0.000004418825,0.000005933087,0.1078416,0.00009520258,0.873953,0.0008084127],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001193918,0.9876416,0.007807337,0.00004647436,0.00009109391,0.002888635,0.00001524804,0.00006163595,0.000254109],"genre_scores_gemma":[0.0002557954,0.9961931,0.0005732133,0.00118844,0.0001874922,0.0004901675,0.000342399,0.0002755974,0.0004938079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9845851,"threshold_uncertainty_score":0.9995381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0919764287457091,"score_gpt":0.3806036980557098,"score_spread":0.2886272693100007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}