{"id":"W2039687494","doi":"10.1038/mt.2009.283","title":"Intelligent Design: Combination Therapy With Oncolytic Viruses","year":2009,"lang":"en","type":"review","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":209,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Toronto General Hospital; McMaster University; University of Toronto","funders":"","keywords":"Oncolytic virus; Virotherapy; Radiation therapy; Medicine; Disease; Modalities; Clinical trial; Combination therapy; Cancer; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000450451,0.001098983,0.001454674,0.001065702,0.0002283945,0.000949859,0.001239651,0.001033985,0.0009404378],"category_scores_gemma":[0.0003249847,0.00039622,0.000438078,0.001165755,0.0006022574,0.000913673,0.0005749155,0.001616153,0.0009857565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007187856,"about_ca_system_score_gemma":0.0003421403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004950511,"about_ca_topic_score_gemma":0.0008064382,"domain_scores_codex":[0.9997938,0.00003606383,0.00001493508,0.00004178633,0.00009184759,0.00002156505],"domain_scores_gemma":[0.9999235,0.00003516836,0.00001339804,0.000004925142,0.00001710191,0.000006008408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001075705,0.0001625557,0.0001395652,0.005697101,0.00008360885,0.0003141108,0.00006982078,0.002123012,0.03450915,0.01266923,0.009909779,0.9342146],"study_design_scores_gemma":[0.00005435697,0.0002676618,0.0004566192,0.0009175492,0.0001216645,0.002031989,0.00003769984,0.002102681,0.03260455,0.006038642,0.9553168,0.00004974091],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001461279,0.9835054,0.01105606,0.000249105,0.0004010453,0.00003251426,0.00002136412,0.00006313695,0.003210115],"genre_scores_gemma":[0.01156776,0.9719963,0.01125814,0.0003357017,0.0002484234,0.00007864508,0.00007851567,0.00001697659,0.004419426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001454674,"threshold_uncertainty_score":0.005215168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0919764287457091,"score_gpt":0.3806036980557098,"score_spread":0.2886272693100007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}