{"id":"W2039716262","doi":"10.1016/j.bbalip.2014.10.008","title":"Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid","year":2014,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":327,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; American Asthma Foundation","keywords":"Hydroxyeicosatetraenoic acid; Arachidonic acid; Lipoxygenase; Biochemistry; Chemistry; Lipid signaling; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003588871,0.0006268863,0.001053741,0.001456354,0.0002084967,0.0007802976,0.0006612524,0.0006709984,0.001990433],"category_scores_gemma":[0.000413727,0.0002887501,0.0003248196,0.0016808,0.0004254429,0.001098381,0.0004177574,0.001174709,0.00105868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004021535,"about_ca_system_score_gemma":0.0007488314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009659749,"about_ca_topic_score_gemma":0.001763466,"domain_scores_codex":[0.9999014,0.00001208137,0.00001848238,0.00002030961,0.00003676537,0.00001099985],"domain_scores_gemma":[0.9998785,0.00005128021,0.0000236277,0.000004124787,0.00003142331,0.00001104106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001752127,0.00009067258,0.0004203102,0.01942017,0.0001277516,0.0003319785,0.00007847372,0.0003688082,0.007526006,0.004209142,0.01423553,0.9530159],"study_design_scores_gemma":[0.00003425014,0.0001377502,0.002033966,0.002558235,0.0002326141,0.001864992,0.0001040268,0.00009431575,0.002237572,0.002165778,0.9885066,0.00002984167],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002210777,0.998913,0.0001196625,0.0001282733,0.00007337295,0.00000331054,0.00002036237,0.000003331053,0.0005175138],"genre_scores_gemma":[0.0007851176,0.998386,0.0001888495,0.00007939954,0.00007382713,0.000004471703,0.00002383786,5.857119e-7,0.0004578666],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001990433,"threshold_uncertainty_score":0.006658673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249918707911434,"score_gpt":0.2634300612955017,"score_spread":0.2509308742163873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}