{"id":"W2039716262","doi":"10.1016/j.bbalip.2014.10.008","title":"Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid","year":2014,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":327,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; American Asthma Foundation","keywords":"Hydroxyeicosatetraenoic acid; Arachidonic acid; Lipoxygenase; Biochemistry; Chemistry; Lipid signaling; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0004971597,0.001364001,0.003507061,0.0003609188,0.0001640349,0.00004523956,0.0007283828,0.002118859,0.00002143918],"category_scores_gemma":[0.000186014,0.001080442,0.0008049507,0.0002953961,0.001945172,0.00001585783,0.0009196274,0.0007252882,0.000006192323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001972409,"about_ca_system_score_gemma":0.000195716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003430792,"about_ca_topic_score_gemma":0.000003323421,"domain_scores_codex":[0.9941764,0.001502347,0.001346552,0.001966455,0.0001992983,0.0008088719],"domain_scores_gemma":[0.9969494,0.0004621867,0.001098673,0.0009561828,0.000122491,0.0004110873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001342175,0.0002863954,0.00004654782,0.002626675,0.0008928268,0.000005787869,0.0000370407,7.840411e-8,0.9493844,0.00007401078,0.00008282997,0.04642918],"study_design_scores_gemma":[0.001349652,0.002721025,0.0002951426,0.0008145986,0.001674589,0.00003541167,0.00002115242,0.00001086781,0.9287527,0.000156394,0.06298414,0.00118434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5280932,0.4706857,0.00003640919,0.0000591594,0.0002913278,0.0005341044,0.00022774,0.0000255392,0.000046782],"genre_scores_gemma":[0.4780143,0.5201278,0.0004416966,0.0002372054,0.0001620768,0.00005119354,0.000876773,0.00008004632,0.000008889204],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0629013,"threshold_uncertainty_score":0.9999111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249918707911434,"score_gpt":0.2634300612955017,"score_spread":0.2509308742163873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}