{"id":"W2039721697","doi":"10.1096/fj.08-121434","title":"Astrocytes recognize intracellular polyinosinic‐polycytidylic acid <i>via</i> MDA‐5","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Intracellular; Extracellular; Cell biology; RNA; Biology; Innate immune system; Molecular biology; Gene expression; Chemistry; Receptor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008345625,0.0004176582,0.0001549225,0.00008066069,0.0001249667,0.0003278911,0.0001254096,0.0002566614,0.0009042331],"category_scores_gemma":[0.00006620582,0.0001183329,0.0002419683,0.00008335754,0.0001585125,0.0001723515,0.0001583566,0.0004396707,0.0005627187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002182897,"about_ca_system_score_gemma":0.0001864036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006656024,"about_ca_topic_score_gemma":0.0009509239,"domain_scores_codex":[0.9998654,0.00002009131,0.00001088523,0.00002671335,0.00003895802,0.00003789458],"domain_scores_gemma":[0.9999421,0.00000745895,0.00001743192,0.000008092128,0.00001107512,0.00001390022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002877854,0.000004524037,0.00008849862,0.00001901457,0.000001943483,0.00003132718,0.000007998307,0.00001573212,0.999404,0.00005304984,0.00001561638,0.0003295311],"study_design_scores_gemma":[0.000006480064,0.0001381097,0.001737193,0.000005510831,0.0000152296,0.0001238994,0.00002405584,0.0003020188,0.9958774,0.00003335907,0.001734862,0.000001889879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848905,0.002386732,0.006853117,0.0001492067,0.00007998363,0.00005093984,0.0003204194,0.0001466973,0.005122407],"genre_scores_gemma":[0.9928561,0.000831634,0.003167984,0.00008392015,0.00001411482,0.00004150816,0.0003457369,0.0000126431,0.002646345],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009042331,"threshold_uncertainty_score":0.003024936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01912075550358177,"score_gpt":0.2247768050281421,"score_spread":0.2056560495245603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}