{"id":"W2039742289","doi":"10.1016/j.bbrc.2007.04.055","title":"Complement activation by islet amyloid polypeptide (IAPP) and α-synuclein 112","year":2007,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Fondation pour la Recherche sur Alzheimer","keywords":"Complement system; Islet; Amyloid (mycology); Complement (music); In vitro; Alternative complement pathway; Synucleinopathies; Complement factor I; Biology; Immunology; Parkinson's disease; Disease; Diabetes mellitus; Cell biology; Neuroscience; Medicine; Biochemistry; Endocrinology; Alpha-synuclein; Pathology; Antibody; Phenotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003261144,0.0004217837,0.0002178207,0.0003581487,0.0002814058,0.0004425679,0.0002108625,0.0006564351,0.001710925],"category_scores_gemma":[0.0004463326,0.0002031269,0.0004058315,0.0001848632,0.000331153,0.0003596422,0.0004226168,0.0005236846,0.0003585949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006604037,"about_ca_system_score_gemma":0.0002644084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001512328,"about_ca_topic_score_gemma":0.0009225528,"domain_scores_codex":[0.9997182,0.00008264685,0.00002068827,0.00002225936,0.00006022913,0.00009594163],"domain_scores_gemma":[0.999856,0.00005194579,0.00002344491,0.00001546154,0.00002398043,0.00002908281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002551382,0.0001222585,0.001758873,0.00009024222,0.00002810205,0.001344984,0.00009233926,0.0002981021,0.9890416,0.001101122,0.0003051484,0.003265879],"study_design_scores_gemma":[0.0002053459,0.001010676,0.02658398,0.00002901487,0.00005648601,0.00309596,0.0002333798,0.004455118,0.9591914,0.001651003,0.003459039,0.00002869793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946423,0.00186004,0.000749874,0.0001327398,0.0000518211,0.00002217366,0.00005652725,0.00001239959,0.002472168],"genre_scores_gemma":[0.9980072,0.0004285988,0.0003726519,0.00003777301,0.0000139208,0.00001055815,0.00009720604,0.000002841287,0.001029172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001710925,"threshold_uncertainty_score":0.005723596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07554805343435089,"score_gpt":0.3779697438736491,"score_spread":0.3024216904392982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}