{"id":"W2039747078","doi":"10.1128/jvi.00089-09","title":"Identification of Integrin α3 as a New Substrate of the Adenovirus E4orf6/E1B 55-Kilodalton E3 Ubiquitin Ligase Complex","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; McGill University","keywords":"Ubiquitin ligase; Biology; Cullin; Ubiquitin; F-box protein; Proteasome; Protein subunit; Cell biology; Molecular biology; Integrin; Cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007320836,0.0001385321,0.0003083303,0.0001291302,0.00004305731,0.00001147613,0.0006270675,0.0001877819,0.0001057728],"category_scores_gemma":[0.0002626239,0.0001031085,0.0002264366,0.0001740053,0.0001974338,0.000007995463,0.00006440416,0.0002998092,0.00001026729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002295635,"about_ca_system_score_gemma":0.0005582181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002562914,"about_ca_topic_score_gemma":0.00009177882,"domain_scores_codex":[0.9982345,0.0002840556,0.0007913037,0.0001708554,0.0002855854,0.0002337472],"domain_scores_gemma":[0.9982818,0.00002947411,0.0008567835,0.000413524,0.0002902975,0.0001280644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002970333,0.0001797396,0.0004826731,0.0000107226,0.00008338186,0.000006054833,0.00007890548,0.0002208229,0.9896458,0.0001593547,0.001804471,0.004357782],"study_design_scores_gemma":[0.001047903,0.004833367,0.01619647,0.00001965805,0.00003596461,0.0001421488,0.00005676235,0.00003471513,0.9746494,0.001697599,0.001203319,0.00008263608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946108,0.001077397,0.0002163049,0.003650293,0.0001250823,0.0001396514,0.00001102864,0.000002179046,0.0001672153],"genre_scores_gemma":[0.9982269,0.0003724653,0.0001165784,0.0007287945,0.0002452266,0.000001134097,0.000006416527,0.00001326131,0.000289259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0157138,"threshold_uncertainty_score":0.4204643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02487125676722987,"score_gpt":0.3265730373738379,"score_spread":0.301701780606608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}