{"id":"W2039750668","doi":"10.1007/s00520-014-2142-2","title":"The effects of denosumab on calcium profiles in advanced cancer patients with bone metastases","year":2014,"lang":"en","type":"article","venue":"Supportive Care in Cancer","topic":"Bone health and treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Response Biomedical (Canada); Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Amgen","keywords":"Medicine; Denosumab; Pain medicine; Cancer; Bone Density Conservation Agents; Bone metastasis; Internal medicine; Bisphosphonate; Osteoporosis; Oncology; Calcium; Prostate cancer; Bone mineral; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000380222,0.0002257428,0.0008629181,0.0002859813,0.0002545614,0.000393051,0.0001757953,0.0004156978,0.001190942],"category_scores_gemma":[0.001749139,0.0001425016,0.0005879769,0.0004747789,0.0001752158,0.0002837237,0.0002329476,0.0006912418,0.0001525479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003575509,"about_ca_system_score_gemma":0.0004537368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004459378,"about_ca_topic_score_gemma":0.010521,"domain_scores_codex":[0.9997193,0.0001044483,0.00003193966,0.00002325395,0.00006308903,0.00005796391],"domain_scores_gemma":[0.999531,0.0001579643,0.0001158193,0.00001850333,0.00005362884,0.0001230649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3074095,0.004528685,0.4194133,0.0007385042,0.003035953,0.001014854,0.0004946518,0.001321004,0.0204713,0.0001659123,0.001565454,0.2398409],"study_design_scores_gemma":[0.006138539,0.02596175,0.9598932,0.00007248672,0.001610199,0.0006132579,0.0004134853,0.0007646073,0.001674154,0.0001956923,0.002629712,0.00003304992],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920309,0.006523046,0.00003105712,0.0002569628,0.0000246591,0.00002334647,0.0001586646,0.000005699782,0.0009457283],"genre_scores_gemma":[0.9973871,0.001701982,0.00009072949,0.0001706199,0.00004634539,0.00001090578,0.0001922493,0.000001963116,0.0003980313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004459378,"threshold_uncertainty_score":0.008866847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009346742577915549,"score_gpt":0.3231976766488251,"score_spread":0.3138509340709096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}