{"id":"W2039763889","doi":"10.1038/nprot.2010.102","title":"Chromosome orientation fluorescence in situ hybridization to study sister chromatid segregation in vivo","year":2010,"lang":"en","type":"article","venue":"Nature Protocols","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Sister chromatids; Chromatid; Biology; Sister chromatid exchange; Genetics; Molecular biology; Fluorescence in situ hybridization; Cell division; Cell biology; Chromosome; DNA; Cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009967729,0.0006856518,0.0005765922,0.0008183608,0.001059506,0.0008790336,0.001106125,0.0009336873,0.00554393],"category_scores_gemma":[0.0003191857,0.0009882442,0.0006247617,0.0005863117,0.0007083066,0.0007715553,0.0007602398,0.003066778,0.002728045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001181132,"about_ca_system_score_gemma":0.0008867249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002636244,"about_ca_topic_score_gemma":0.008414342,"domain_scores_codex":[0.9995167,0.00009089382,0.00002879725,0.0001332242,0.0001545235,0.00007579017],"domain_scores_gemma":[0.9997012,0.0001036708,0.00002726686,0.000089459,0.00003720556,0.00004116003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002093983,0.00001643387,0.00004477019,0.00003313049,0.000004020281,0.00001800094,0.00001843063,0.00004921993,0.9965951,0.001065048,0.0002126341,0.001922218],"study_design_scores_gemma":[0.00003312236,0.00005669874,0.001216183,0.0000101817,0.00002116456,0.000310699,0.0000268276,0.001498211,0.98101,0.0005076641,0.01529789,0.00001130997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"protocol","genre_scores_codex":[0.1695219,0.004766202,0.7902909,0.001774579,0.0007113207,0.0006412301,0.002513748,0.002151093,0.02762902],"genre_scores_gemma":[0.4277264,0.006940337,0.506557,0.001078709,0.0002061997,0.001101973,0.005017163,0.001872176,0.04950003],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.00554393,"threshold_uncertainty_score":0.01854622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005315148000593736,"score_gpt":0.2863727358190029,"score_spread":0.2810575878184092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}