{"id":"W2039781951","doi":"10.1097/00001721-200408000-00002","title":"Improving upon the in vitro biological activity of antithrombotic disulfides","year":2004,"lang":"en","type":"article","venue":"Blood Coagulation & Fibrinolysis","topic":"Garlic and Onion Studies","field":"Agricultural and Biological Sciences","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Allison University; University of Calgary","funders":"","keywords":"Chemistry; Lipophilicity; Antithrombotic; In vitro; Biological activity; Platelet aggregation; Disulfide bond; Platelet; Nitro; Platelet aggregation inhibitor; Potency; Ring (chemistry); Stereochemistry; Pharmacology; Combinatorial chemistry; Biochemistry; Organic chemistry; Aspirin; Medicine; Alkyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002632777,0.0005637511,0.0002480141,0.0002457075,0.0001549587,0.0001954297,0.000113231,0.0001728289,0.0009280571],"category_scores_gemma":[0.0002070647,0.0000808025,0.0002708846,0.0001597117,0.0001415958,0.000124749,0.0001285106,0.0002326103,0.0001319432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001024392,"about_ca_system_score_gemma":0.0001409659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003126117,"about_ca_topic_score_gemma":0.0006162778,"domain_scores_codex":[0.9998639,0.00004985099,0.00001312422,0.00001529715,0.00003002662,0.00002779425],"domain_scores_gemma":[0.9999025,0.00003040435,0.00002352587,0.000007772508,0.00001638865,0.00001946665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001874156,0.00003844416,0.0001890729,0.00007556453,0.000009781841,0.00005162291,0.00002429056,0.00008264885,0.9964509,0.00004659078,0.00001473372,0.002829014],"study_design_scores_gemma":[0.000007300765,0.001030755,0.0007720119,0.000005170525,0.00002933383,0.00009565166,0.000009229841,0.00008771523,0.9971074,0.00001065284,0.0008431289,0.000001593775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932427,0.004472687,0.0009527129,0.00004681617,0.0000182383,0.00001779441,0.00005975723,0.00001606788,0.001173234],"genre_scores_gemma":[0.9942375,0.002948321,0.001363351,0.00003805045,0.00002231659,0.00001063438,0.0002286378,0.00000716566,0.001143974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009280571,"threshold_uncertainty_score":0.003104627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02963957035342476,"score_gpt":0.2281969633170795,"score_spread":0.1985573929636547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}