{"id":"W2039807807","doi":"10.1371/journal.pone.0041726","title":"Burkholderia cenocepacia Type VI Secretion System Mediates Escape of Type II Secreted Proteins into the Cytoplasm of Infected Macrophages","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; Cystic Fibrosis Canada","keywords":"Secretion; Burkholderia cenocepacia; Pyroptosis; Cell biology; Biology; Type VI secretion system; Inflammasome; Microbiology; Cytoplasm; Phagosome; Intracellular; Vacuole; Burkholderia; Virulence; Bacteria; Biochemistry; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700637,0.0001480718,0.0002712455,0.00004761812,0.0001046428,0.000008581985,0.0001855432,0.0001364093,0.00005350626],"category_scores_gemma":[0.000552622,0.000108386,0.00004675045,0.0002392413,0.0001590871,0.000008291192,0.0002942674,0.00009628994,0.000011343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002482538,"about_ca_system_score_gemma":0.00007128914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005848885,"about_ca_topic_score_gemma":0.00002437911,"domain_scores_codex":[0.998877,0.0001470321,0.0002519673,0.0001714023,0.0002767142,0.0002758734],"domain_scores_gemma":[0.9988872,0.00002778432,0.0001689487,0.0003551971,0.0004889687,0.00007187542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000201168,0.000244073,0.008229096,0.000418406,0.0004463284,4.327595e-7,0.000612884,0.000001308996,0.9896827,0.00003641038,0.00006975358,0.00005743513],"study_design_scores_gemma":[0.0003223,0.0008107949,0.01311587,0.0001323218,0.00008530928,0.000001434959,0.0002213168,0.00006331022,0.984947,0.000005259342,0.0001812387,0.0001138588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972154,0.001725753,0.0000136173,0.00007610377,0.00008319978,0.0005168403,0.00002348664,0.00002177035,0.0003237654],"genre_scores_gemma":[0.9985059,0.0004507401,0.000492324,0.000009133853,0.0002155077,0.00003850111,0.0001404658,0.00002430725,0.0001230942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004886771,"threshold_uncertainty_score":0.4419854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110183277104662,"score_gpt":0.2425965449525854,"score_spread":0.2214947121815388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}