{"id":"W2039807807","doi":"10.1371/journal.pone.0041726","title":"Burkholderia cenocepacia Type VI Secretion System Mediates Escape of Type II Secreted Proteins into the Cytoplasm of Infected Macrophages","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; Cystic Fibrosis Canada","keywords":"Secretion; Burkholderia cenocepacia; Pyroptosis; Cell biology; Biology; Type VI secretion system; Inflammasome; Microbiology; Cytoplasm; Phagosome; Intracellular; Vacuole; Burkholderia; Virulence; Bacteria; Biochemistry; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158244,0.0003382076,0.0002664558,0.0001448602,0.0001206976,0.0003817711,0.0001475558,0.0002665693,0.000638094],"category_scores_gemma":[0.0001604335,0.0001235687,0.0002290461,0.0001196625,0.0001526104,0.0001818407,0.0002736241,0.0004256928,0.000520004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002210235,"about_ca_system_score_gemma":0.000211807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005072356,"about_ca_topic_score_gemma":0.0003713304,"domain_scores_codex":[0.999827,0.00003351939,0.00002208813,0.00002570213,0.00004232519,0.00004946297],"domain_scores_gemma":[0.9998685,0.00001930699,0.00004201331,0.0000230868,0.00001693106,0.00003017799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003371347,0.000006037814,0.0001319241,0.00001065408,0.000001343088,0.00003399701,0.000007830146,0.0000106302,0.9995776,0.00001951789,0.000007425243,0.0001594238],"study_design_scores_gemma":[0.00001513904,0.0001482395,0.005958262,0.000006022695,0.000006551041,0.000438555,0.00005280948,0.0005678014,0.9918641,0.00004431302,0.0008942095,0.000004041279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996743,0.0006487893,0.001658175,0.00008509502,0.00001588477,0.00001702674,0.0002669652,0.00004046786,0.0005246083],"genre_scores_gemma":[0.9971208,0.0002956375,0.001186419,0.0000371578,0.000005398279,0.00001933355,0.0004242929,0.000009775198,0.0009011056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000638094,"threshold_uncertainty_score":0.002134621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110183277104662,"score_gpt":0.2425965449525854,"score_spread":0.2214947121815388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}