{"id":"W2039864949","doi":"10.1023/a:1015832302721","title":"Pharming vaccines for hepatitis and cytomegalovirus: Towards the development of multivalent and subunit vaccines for oral delivery of antigens","year":2002,"lang":"en","type":"article","venue":"Phytochemistry Reviews","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Agriculture and Agri-Food Canada; Canadian Science Centre for Human and Animal Health; Health Canada; University of Ottawa","funders":"National Research Council Canada; Health Canada; Natural Sciences and Engineering Research Council of Canada; Sick Kids Foundation","keywords":"Virology; Biology; Hepatitis B virus; Antigen; Protein subunit; Duck hepatitis B virus; Transformation (genetics); Genetically modified crops; Virus-like particle; Virus; Expression cassette; Transgene; Gene; Hepadnaviridae; Vector (molecular biology); Recombinant DNA; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003745429,0.0004296606,0.000387154,0.0003424681,0.0001721595,0.0006071267,0.0002605002,0.0006190561,0.001391326],"category_scores_gemma":[0.0001893387,0.0001835181,0.0002078427,0.0002351354,0.0004472511,0.0007049761,0.000326419,0.001027787,0.0008133895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005789693,"about_ca_system_score_gemma":0.0004428863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004647775,"about_ca_topic_score_gemma":0.0006426558,"domain_scores_codex":[0.9999017,0.00001530544,0.000004566953,0.00001616971,0.00004097885,0.00002130855],"domain_scores_gemma":[0.9999177,0.00002108948,0.00001932784,0.000006146759,0.00001686852,0.0000188241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008950054,0.000109387,0.0001776014,0.0004160465,0.000009801307,0.00007818185,0.0000526127,0.0005136262,0.8639002,0.003817874,0.001000426,0.1298347],"study_design_scores_gemma":[0.00004541594,0.001146973,0.000848193,0.00008467791,0.00005184852,0.0007167653,0.00006653592,0.001535238,0.8921094,0.002737151,0.1006409,0.00001683588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4688311,0.3241966,0.1819654,0.00600792,0.001096318,0.0003322321,0.0002501292,0.0006718276,0.01664841],"genre_scores_gemma":[0.6432899,0.2456493,0.07247523,0.00180246,0.000516158,0.0001957301,0.0004092594,0.0001657471,0.03549614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001391326,"threshold_uncertainty_score":0.004654408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07407601617539863,"score_gpt":0.3070098152624153,"score_spread":0.2329337990870167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}