{"id":"W2039920681","doi":"10.1111/acel.12155","title":"Collagenase‐resistant collagen promotes mouse aging and vascular cell senescence","year":2013,"lang":"en","type":"article","venue":"Aging Cell","topic":"Bone and Dental Protein Studies","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Senescence; Biology; Type I collagen; Collagenase; Wild type; Downregulation and upregulation; Cell biology; Mutant; Endocrinology; Internal medicine; Biochemistry; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000415914,0.0004791741,0.0002730081,0.0006577079,0.0001693568,0.0003438931,0.0001792124,0.0004475656,0.001876022],"category_scores_gemma":[0.000142245,0.0003243103,0.0004445783,0.0002037389,0.0002104835,0.0001815174,0.0002087624,0.0009098107,0.0005279782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002501262,"about_ca_system_score_gemma":0.0001326188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003954029,"about_ca_topic_score_gemma":0.0005929862,"domain_scores_codex":[0.9997026,0.00007114336,0.00003569345,0.00006319841,0.00005290456,0.00007431425],"domain_scores_gemma":[0.999612,0.00004305612,0.000144572,0.00005232556,0.00002600203,0.0001221284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001222021,0.00004900263,0.0001989891,0.00001243655,0.000003750369,0.00003691882,0.00001445122,0.00001501701,0.9990277,0.00004979288,0.0000194935,0.0004502753],"study_design_scores_gemma":[0.00007189943,0.002231517,0.0140746,0.00001995348,0.00003180453,0.0009559623,0.00004605067,0.0008522848,0.9775024,0.0001080273,0.004096072,0.000009397871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931874,0.002140396,0.002393929,0.0001235047,0.00004731185,0.00003847696,0.0004163475,0.0001541556,0.001498421],"genre_scores_gemma":[0.9901542,0.001466217,0.002282729,0.00009728825,0.00002555158,0.00008372435,0.0008442515,0.00004715494,0.004998904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001876022,"threshold_uncertainty_score":0.006275952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008841646567340962,"score_gpt":0.2166902945672034,"score_spread":0.2078486479998624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}