{"id":"W2040030839","doi":"10.1002/wrna.1111","title":"Current advances in Phi29 pRNA biology and its application in drug delivery","year":2012,"lang":"en","type":"review","venue":"Wiley Interdisciplinary Reviews - RNA","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"DNA; Bacteriophage; RNA; Computational biology; Biology; Drug delivery; Small molecule; Aptamer; Flexibility (engineering); Biophysics; Nucleic acid; Antiviral drug; Drug; Cell biology; Chemistry; Nanotechnology; Biochemistry; Gene; Genetics; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000795054,0.0006095247,0.001743565,0.0003144055,0.00006442991,0.00001459717,0.0003967662,0.0003668154,0.000002451098],"category_scores_gemma":[0.00003655845,0.0004552849,0.0004137853,0.0003951135,0.0001166114,0.0000252816,0.0008982533,0.000483367,0.00002300921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001000827,"about_ca_system_score_gemma":0.00005692964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004156551,"about_ca_topic_score_gemma":0.0002474278,"domain_scores_codex":[0.9968492,0.0004620181,0.001213169,0.0009170304,0.00008433454,0.0004742639],"domain_scores_gemma":[0.9985514,0.00003308629,0.0006908555,0.0005666213,0.00004481334,0.0001132202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001241877,0.0001222971,0.00006067751,0.00429363,0.00002046539,0.000001896704,0.0000220136,1.153834e-7,0.0004326148,0.00002168688,0.0001678,0.9948444],"study_design_scores_gemma":[0.0001085359,0.00008430815,0.000005969605,0.01168135,0.0002014618,0.00003173653,0.000009291356,0.000008728683,0.0001875384,0.000158323,0.987017,0.000505727],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004405673,0.9975594,0.0001354938,0.00002595228,0.0001700923,0.001380632,0.00005378794,0.00002168812,0.0002123687],"genre_scores_gemma":[0.003522276,0.994337,0.0003383608,0.0000235789,0.0004071469,0.0004727949,0.0008111319,0.00004485277,0.00004284922],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9943386,"threshold_uncertainty_score":0.9997899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03227675006593841,"score_gpt":0.391312408813822,"score_spread":0.3590356587478836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}