{"id":"W2040114686","doi":"10.3899/jrheum.120005","title":"Risk of Failure of a Clinical Drug Trial in Patients with Moderate to Severe Rheumatoid Arthritis","year":2012,"lang":"en","type":"review","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"AstraZeneca; Amgen; Abbott Laboratories","keywords":"Medicine; Rheumatoid arthritis; Drug; Clinical trial; Internal medicine; Arthritis; Drug trial; Surgery; Physical therapy; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.01470759,0.0008182505,0.005362355,0.007055636,0.0003607544,0.001738933,0.00124211,0.00175954,0.002255368],"category_scores_gemma":[0.06343623,0.0006642687,0.005244956,0.006421911,0.0007284883,0.001626567,0.0008859269,0.0009367767,0.0002073783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001678839,"about_ca_system_score_gemma":0.00444362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002209154,"about_ca_topic_score_gemma":0.005358923,"domain_scores_codex":[0.9807193,0.007968774,0.006806605,0.001069875,0.003216004,0.0002194754],"domain_scores_gemma":[0.892134,0.08329033,0.01923872,0.0009390313,0.003721866,0.00067606],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001250516,0.00003929126,0.01123616,0.8094323,0.03467531,0.0004674098,0.0002854379,0.0002534432,0.0003276666,0.0005306379,0.003381156,0.1381205],"study_design_scores_gemma":[0.001458862,0.001394383,0.03770023,0.6547344,0.2481611,0.004520481,0.0006000959,0.0004846827,0.0006799118,0.001399646,0.04876172,0.0001044105],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001739218,0.9973384,0.0001421314,0.0001972725,0.00004789056,0.000104828,0.0001369577,0.000004204717,0.0002890267],"genre_scores_gemma":[0.06222671,0.9352254,0.001024522,0.0006317194,0.0001537402,0.0003307622,0.000275615,0.000006095881,0.0001253861],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9852924,"threshold_uncertainty_score":0.07778215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03242831128092578,"score_gpt":0.3373152867083025,"score_spread":0.3048869754273767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}