{"id":"W2040118875","doi":"10.1039/b406490a","title":"Mechanistic analogies amongst carbohydrate modifying enzymes","year":2004,"lang":"en","type":"review","venue":"Chemical Communications","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Networks of Centres of Excellence of Canada; Michael Smith Health Research BC","keywords":"Rational design; Glycosidic bond; Glycosyltransferase; Enzyme; Function (biology); Computational biology; Orchestration; Biochemistry; Chemistry; Biology; Biochemical engineering; Computer science; Cell biology; Genetics; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007716552,0.0009046295,0.000925648,0.001146955,0.0005034066,0.00165305,0.001640064,0.001534505,0.004122179],"category_scores_gemma":[0.0006191497,0.0003956672,0.0004900447,0.001273204,0.00195513,0.002701118,0.001306322,0.002890705,0.002634381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001305503,"about_ca_system_score_gemma":0.0006865528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003832452,"about_ca_topic_score_gemma":0.000438843,"domain_scores_codex":[0.9996614,0.00006595031,0.00002854376,0.00009157839,0.0001049591,0.00004738748],"domain_scores_gemma":[0.9998628,0.0000593135,0.00002067976,0.00002369324,0.00001855868,0.00001493406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001737475,0.000166298,0.0003404797,0.006625775,0.000112952,0.002624032,0.0004117073,0.003299448,0.02753032,0.4280809,0.013089,0.5175453],"study_design_scores_gemma":[0.00002739981,0.0000811171,0.000286728,0.0004240087,0.00002509409,0.002901827,0.00006374592,0.0002592558,0.00538351,0.07070326,0.9198194,0.00002465999],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003857662,0.9372382,0.008820349,0.002373104,0.001580865,0.00006377033,0.0000627976,0.00008760413,0.04591567],"genre_scores_gemma":[0.03516574,0.9433359,0.004635662,0.001999255,0.001052341,0.0001367993,0.0001137796,0.00001403722,0.01354649],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004122179,"threshold_uncertainty_score":0.01379001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1043244341628396,"score_gpt":0.3350927396116177,"score_spread":0.230768305448778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}