{"id":"W2040201361","doi":"10.1158/1538-7445.am2012-4423","title":"Abstract 4423: Transgenic liver expression of human arylamine <i>N</i>-acetyltransferase NAT2 restores sensitivity of male Nat1/2 null mice to 4-aminobiphenyl-induced liver tumorigenesis","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Biopolymer Synthesis and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Genetically modified mouse; Carcinogen; Carcinogenesis; Endocrinology; Internal medicine; Ratón; Liver tumor; Biology; Transgene; Medicine; Cancer; Hepatocellular carcinoma; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008625744,0.0001804505,0.0002581059,0.0001203162,0.0001588857,0.00001015657,0.0002813263,0.0001866706,0.0002639585],"category_scores_gemma":[0.00004575747,0.0001704399,0.0001366712,0.000258974,0.0001992058,0.00001401275,0.00009882853,0.0001967538,0.00001194726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003984333,"about_ca_system_score_gemma":0.0001256615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001535432,"about_ca_topic_score_gemma":0.000576221,"domain_scores_codex":[0.9981578,0.0002148798,0.0003176372,0.0004036998,0.0004102733,0.0004956841],"domain_scores_gemma":[0.9987643,0.00008973184,0.00007226232,0.0005465681,0.0002944961,0.0002326161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001767701,0.0003211273,0.0009696066,0.0002011497,0.00003367976,0.000002456676,0.0003394223,0.000003377615,0.9940439,0.00003087571,0.001166304,0.002711298],"study_design_scores_gemma":[0.0002519295,0.0001529631,0.0165936,0.00008927975,0.00001579181,0.000004512357,0.0001644661,0.000002100144,0.9798512,0.000001899331,0.002691668,0.0001805945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940739,0.004482431,0.0001154794,0.0001156825,0.000059879,0.0004334235,0.0001982158,0.000007634732,0.0005133558],"genre_scores_gemma":[0.9979836,0.0008699453,0.000154084,0.00003506352,0.0003134423,0.0001589801,0.00003654753,0.00003704856,0.0004112709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01562399,"threshold_uncertainty_score":0.6950338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06686798213280928,"score_gpt":0.3600312287630322,"score_spread":0.293163246630223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}