{"id":"W2040201361","doi":"10.1158/1538-7445.am2012-4423","title":"Abstract 4423: Transgenic liver expression of human arylamine <i>N</i>-acetyltransferase NAT2 restores sensitivity of male Nat1/2 null mice to 4-aminobiphenyl-induced liver tumorigenesis","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Biopolymer Synthesis and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Genetically modified mouse; Carcinogen; Carcinogenesis; Endocrinology; Internal medicine; Ratón; Liver tumor; Biology; Transgene; Medicine; Cancer; Hepatocellular carcinoma; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000204815,0.0009706199,0.0003826647,0.0008834032,0.0002656339,0.0003574239,0.0004005143,0.0005455082,0.005681668],"category_scores_gemma":[0.0001117913,0.0004081666,0.0005351732,0.0002230422,0.0004775322,0.0002671439,0.0002742517,0.0009149772,0.001512528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003699056,"about_ca_system_score_gemma":0.0002488749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001404674,"about_ca_topic_score_gemma":0.002527624,"domain_scores_codex":[0.9996512,0.00004703894,0.00004266158,0.00007385741,0.0001174798,0.00006777201],"domain_scores_gemma":[0.9996006,0.00003723302,0.0001604292,0.00003405575,0.00002436283,0.0001433863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001314257,0.00004505277,0.0001229784,0.00001279172,0.000004719993,0.00005736818,0.000007695846,0.00002390684,0.9992031,0.00004997394,0.0000415583,0.0002993591],"study_design_scores_gemma":[0.000059833,0.0005450588,0.004344744,0.00000845566,0.00002180391,0.0005969363,0.00003455974,0.0004874234,0.9918813,0.00003279204,0.001978148,0.000008964202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893699,0.0005660129,0.004454053,0.0002092567,0.00009688161,0.00009618709,0.002603798,0.0004155484,0.002188438],"genre_scores_gemma":[0.9641423,0.0007986333,0.005911981,0.0002238877,0.00006084243,0.0002222603,0.004103589,0.0004376608,0.02409891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005681668,"threshold_uncertainty_score":0.01900709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06686798213280928,"score_gpt":0.3600312287630322,"score_spread":0.293163246630223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}