{"id":"W2040231972","doi":"10.1002/1521-4141(2000)30:8<2235::aid-immu2235>3.0.co;2-9","title":"Leishmania donovani promastigotes evade the activation of mitogen-activated protein kinases p38, c-Jun N-terminal kinase, and extracellular signal-regulated kinase-1/2 during infection of naive macrophages","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec; Institut National de la Recherche Scientifique","funders":"","keywords":"Biology; MAPK/ERK pathway; Cell biology; Leishmania donovani; Kinase; p38 mitogen-activated protein kinases; Proinflammatory cytokine; Signal transduction; Mitogen-activated protein kinase; Protein kinase A; MAP kinase kinase kinase; Immunology; Visceral leishmaniasis; Inflammation; Leishmaniasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001734292,0.0005932684,0.0002435998,0.0001514625,0.0001386308,0.0002528167,0.0001769075,0.0002318163,0.0008353872],"category_scores_gemma":[0.0001107417,0.000212736,0.000194634,0.00007256022,0.0001996598,0.0001891129,0.0002143213,0.0004045023,0.0003511079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188572,"about_ca_system_score_gemma":0.0001627893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002697796,"about_ca_topic_score_gemma":0.0005204597,"domain_scores_codex":[0.999842,0.00002828452,0.00001282547,0.0000205456,0.00003386344,0.00006238285],"domain_scores_gemma":[0.999943,0.000009936663,0.00001280723,0.000008798225,0.000009705647,0.00001580878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001249683,0.00002953533,0.0001034798,0.00004698185,0.000002265192,0.00004491966,0.00001097826,0.00001938408,0.9991254,0.00004790149,0.00001520757,0.0004289908],"study_design_scores_gemma":[0.00005960534,0.0006592782,0.006314388,0.00001358766,0.00001555711,0.0006760788,0.00004812371,0.0006976939,0.9893679,0.00009953859,0.002043898,0.000004410535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962276,0.001316657,0.001126063,0.00006876988,0.00001785907,0.00003513072,0.0001681457,0.00005078255,0.0009890127],"genre_scores_gemma":[0.9952231,0.0008496015,0.001107844,0.00006496997,0.00001386995,0.00006901509,0.0004505666,0.00001036869,0.002210577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008353872,"threshold_uncertainty_score":0.002794683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0168622338807985,"score_gpt":0.2502673274233337,"score_spread":0.2334050935425352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}