{"id":"W2040261396","doi":"10.1038/srep03169","title":"Antioxidant Induces DNA Damage, Cell Death and Mutagenicity in Human Lung and Skin Normal Cells","year":2013,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Tea Polyphenols and Effects","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"DNA damage; Apoptosis; Antioxidant; Programmed cell death; Lung cancer; Cancer research; DNA; Human skin; Cisplatin; Mechanism (biology); Cell; Biology; Chemistry; Cell biology; Molecular biology; Medicine; Biochemistry; Pathology; Genetics; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001764217,0.0002766322,0.0001930651,0.0003491231,0.0001336371,0.0001809787,0.0001227614,0.0002719082,0.001315107],"category_scores_gemma":[0.0001940214,0.00008378021,0.0002043738,0.0001991641,0.0001318115,0.0001031211,0.0001784822,0.0002516734,0.0001918929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001350225,"about_ca_system_score_gemma":0.0001572753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008389518,"about_ca_topic_score_gemma":0.001297512,"domain_scores_codex":[0.999822,0.00004663209,0.00001782697,0.00003536435,0.00005099251,0.00002719888],"domain_scores_gemma":[0.9998997,0.00002142842,0.00002194821,0.00001938042,0.00002397734,0.00001349117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002283178,0.00003547691,0.0006095376,0.00006218653,0.00001797819,0.00009688803,0.00002572677,0.00003910746,0.9958082,0.00003745772,0.00003432027,0.003004751],"study_design_scores_gemma":[0.000014039,0.001045354,0.008723093,0.000008487182,0.00003454351,0.0004833253,0.0000397546,0.0001707688,0.9877643,0.00005708072,0.001656202,0.000003136459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892583,0.006641644,0.002339069,0.0001066844,0.00002918174,0.0000303067,0.0001820066,0.00005730128,0.001355471],"genre_scores_gemma":[0.9958553,0.001662388,0.0007520561,0.00007698036,0.000005682326,0.00001384087,0.0002171108,0.000004754244,0.001411937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001315107,"threshold_uncertainty_score":0.004399478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01036863898773253,"score_gpt":0.2486168218497168,"score_spread":0.2382481828619843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}