{"id":"W2040301051","doi":"10.2174/1381612013397799","title":"Osteoclast Ion Channels Potential Targets for Antiresorptive Drugs.","year":2001,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Inward-rectifier potassium ion channel; Ion channel; Transient receptor potential channel; Chemistry; Light-gated ion channel; Ligand-gated ion channel; Biophysics; Membrane potential; Potassium channel; Voltage-gated ion channel; SK channel; Osteoclast; Cell biology; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007128762,0.0009188703,0.001449963,0.0001404655,0.0001826732,0.00007691804,0.0007183781,0.0006183674,0.0001007935],"category_scores_gemma":[0.0002263612,0.0007979442,0.001122241,0.0002875692,0.0001791752,0.000008128863,0.000391599,0.0006745399,0.0001769761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009780669,"about_ca_system_score_gemma":0.0003919372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.281777e-7,"about_ca_topic_score_gemma":6.517517e-8,"domain_scores_codex":[0.9958469,0.0006285011,0.0008837916,0.001294896,0.0003681356,0.0009777877],"domain_scores_gemma":[0.998322,0.0001459021,0.0003987857,0.0005207947,0.0002029093,0.0004096692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001467542,0.000432225,3.757909e-7,0.003317615,0.0003644286,0.000001698093,0.00001754512,0.00001216282,0.0004114472,0.00002984964,0.0267272,0.9685387],"study_design_scores_gemma":[0.0012714,0.0004118749,3.764997e-8,0.001382281,0.001203355,0.00003753152,0.000009947776,0.0002520855,0.003856066,0.00001902657,0.9907171,0.0008393601],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000005627004,0.900279,0.09087579,0.00002701488,0.004662439,0.003757827,0.0002268806,0.00005119909,0.0001142382],"genre_scores_gemma":[0.0001024704,0.9910245,0.0007752134,0.00004492197,0.005084367,0.0007923591,0.001507073,0.000177466,0.0004916058],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9676993,"threshold_uncertainty_score":0.9994472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207753157392459,"score_gpt":0.4247252500534173,"score_spread":0.3039499343141714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}