{"id":"W2040301051","doi":"10.2174/1381612013397799","title":"Osteoclast Ion Channels Potential Targets for Antiresorptive Drugs.","year":2001,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Inward-rectifier potassium ion channel; Ion channel; Transient receptor potential channel; Chemistry; Light-gated ion channel; Ligand-gated ion channel; Biophysics; Membrane potential; Potassium channel; Voltage-gated ion channel; SK channel; Osteoclast; Cell biology; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002364733,0.0004209226,0.0006198351,0.0004584811,0.0002115747,0.0007741491,0.0003172295,0.000690735,0.005108865],"category_scores_gemma":[0.0001818342,0.0001155795,0.0005344154,0.0003508867,0.0002133665,0.0005399092,0.0003713924,0.000868395,0.001611485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003344782,"about_ca_system_score_gemma":0.0004909437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004269612,"about_ca_topic_score_gemma":0.001444112,"domain_scores_codex":[0.9998353,0.0000189829,0.00001309136,0.00002225757,0.00007691448,0.00003352025],"domain_scores_gemma":[0.9999217,0.00001313812,0.00001897837,0.000003423612,0.00002774929,0.00001504585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001368033,0.0003268271,0.002042977,0.01503426,0.0002811818,0.003398294,0.0001833547,0.0007048977,0.3318517,0.01729654,0.04914474,0.5783671],"study_design_scores_gemma":[0.0004174723,0.00102419,0.004728508,0.0009464889,0.000355805,0.008635778,0.0001430097,0.0005530933,0.04463362,0.004051232,0.9344594,0.00005127246],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01504541,0.9629113,0.003397881,0.002669726,0.001459063,0.0001167056,0.0005234979,0.0001662289,0.01371019],"genre_scores_gemma":[0.104914,0.8666916,0.004380462,0.003854355,0.001000755,0.000153623,0.001149092,0.00003597878,0.01782013],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005108865,"threshold_uncertainty_score":0.01709086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207753157392459,"score_gpt":0.4247252500534173,"score_spread":0.3039499343141714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}