{"id":"W2040389355","doi":"10.4161/cc.5.16.3009","title":"Absence of an Immediate G1/S Checkpoint in Primary MEFs Following &amp;gamma;-irradiation Identifies a Novel Checkpoint Switch","year":2006,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cardiac Imaging and Diagnostics","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"G2-M DNA damage checkpoint; Biology; CHEK1; Gamma irradiation; Cell cycle checkpoint; Cell biology; Cancer research; Cell cycle; Irradiation; Genetics; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172342,0.0003567417,0.0003383581,0.0002389027,0.0001515883,0.0003956085,0.0003103403,0.0003662968,0.001196972],"category_scores_gemma":[0.0001645119,0.0001790027,0.0002401755,0.0001210008,0.0002350928,0.0002415331,0.0002208261,0.0006536919,0.0006611352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003301685,"about_ca_system_score_gemma":0.0002200117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000463099,"about_ca_topic_score_gemma":0.0007755432,"domain_scores_codex":[0.9998497,0.00001249008,0.00002743643,0.00005524648,0.00003094608,0.00002412019],"domain_scores_gemma":[0.9997486,0.00005319725,0.00007052796,0.00004631035,0.00003052028,0.00005078262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005584723,0.000006643091,0.0001997094,0.00001466678,0.000001676506,0.00002839151,0.000007434136,0.0000136874,0.9991755,0.00003885266,0.00001480208,0.0004428244],"study_design_scores_gemma":[0.000006910126,0.0001298849,0.009566584,0.000005856242,0.000008283054,0.0001598684,0.00001398231,0.0002680426,0.9881592,0.00003387425,0.001645114,0.000002370909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823261,0.002376419,0.009800059,0.0001282542,0.00007439741,0.00007613961,0.002789166,0.0003240524,0.002105523],"genre_scores_gemma":[0.9893478,0.0008807823,0.005551993,0.00009551209,0.00001860706,0.0001106927,0.00179074,0.00007492657,0.002128955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001196972,"threshold_uncertainty_score":0.0040043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011598512851779,"score_gpt":0.2493820177504295,"score_spread":0.2392660326219117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}