{"id":"W2040389355","doi":"10.4161/cc.5.16.3009","title":"Absence of an Immediate G1/S Checkpoint in Primary MEFs Following γ-irradiation Identifies a Novel Checkpoint Switch","year":2006,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cardiac Imaging and Diagnostics","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"G2-M DNA damage checkpoint; Biology; CHEK1; Gamma irradiation; Cell cycle checkpoint; Cell biology; Cancer research; Cell cycle; Irradiation; Genetics; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005267689,0.0001879746,0.0004328414,0.0002038265,0.00004667806,0.00003501312,0.00009995334,0.0001014898,0.00002002713],"category_scores_gemma":[0.0002126661,0.0001942399,0.0002288548,0.0003038652,0.00006290107,0.000203988,0.00005342646,0.0002114245,0.00005274425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001708684,"about_ca_system_score_gemma":0.0001451862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001852872,"about_ca_topic_score_gemma":0.0001818646,"domain_scores_codex":[0.9983318,0.00003038841,0.0005657233,0.0003439185,0.0003908416,0.0003373587],"domain_scores_gemma":[0.9990511,0.0001433721,0.0001725348,0.0004379351,0.00008140102,0.0001136363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009502799,0.000971777,0.1162181,0.0003676417,0.00002912744,0.00008386399,0.001365633,0.001099337,0.878276,0.00003432237,0.0005069818,0.0009521315],"study_design_scores_gemma":[0.0029025,0.0000562585,0.879092,0.0002011683,0.00009787069,0.00002005981,0.0002105935,0.0008709371,0.1152971,0.000581275,0.0004207646,0.0002494909],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884636,0.0008237761,0.0006931838,0.0002164228,0.0005097856,0.0003001461,0.0000132472,0.00007101461,0.008908867],"genre_scores_gemma":[0.9960129,0.00002958814,0.002710227,0.0001340194,0.0002803413,0.0000217297,0.0001812735,0.00003721204,0.0005926826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7629789,"threshold_uncertainty_score":0.7920872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011598512851779,"score_gpt":0.2493820177504295,"score_spread":0.2392660326219117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}