{"id":"W2040496372","doi":"10.1016/j.bbamem.2005.04.007","title":"Membrane topology of loop 13–14 of the Na+/glucose cotransporter (SGLT1): A SCAM and fluorescent labelling study","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Cotransporter; Xenopus; Cysteine; Fluorescence; Mutant; Labelling; Chemistry; Biochemistry; Biophysics; Transmembrane domain; Amino acid; Biology; Physics; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001502079,0.0001110642,0.0001497187,0.0001511218,0.0003077663,0.0002387137,0.000304245,0.0003667172,0.001028275],"category_scores_gemma":[0.0002133702,0.0001486042,0.0002160887,0.000134636,0.0002465881,0.0004273228,0.0001577144,0.0004401709,0.0002777533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005438352,"about_ca_system_score_gemma":0.0001708831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001364595,"about_ca_topic_score_gemma":0.001084488,"domain_scores_codex":[0.9999489,0.000009799437,0.000004002137,0.0000128076,0.0000113089,0.00001311149],"domain_scores_gemma":[0.9998779,0.00003377249,0.00003680717,0.00001199088,0.00002065711,0.00001884818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002976384,0.00002289365,0.0006940312,0.00004229457,0.000006769731,0.0001348106,0.00008199829,0.0003585537,0.9960809,0.0006677234,0.0001031345,0.001509231],"study_design_scores_gemma":[0.00003895558,0.0002292437,0.02019158,0.00002416241,0.00005019317,0.0007061991,0.000183852,0.02059137,0.9507386,0.0004097919,0.006812877,0.00002314873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946747,0.0004537459,0.003369284,0.0001091062,0.00001231413,0.000007908685,0.0001544931,0.00002609467,0.001192216],"genre_scores_gemma":[0.9946895,0.0004573585,0.003112777,0.00004699704,0.00000570956,0.000009404994,0.0004065109,0.00001855794,0.001253188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001364595,"threshold_uncertainty_score":0.003945827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008319338759432604,"score_gpt":0.2336848092871431,"score_spread":0.2253654705277105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}