{"id":"W2040496372","doi":"10.1016/j.bbamem.2005.04.007","title":"Membrane topology of loop 13–14 of the Na+/glucose cotransporter (SGLT1): A SCAM and fluorescent labelling study","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Cotransporter; Xenopus; Cysteine; Fluorescence; Mutant; Labelling; Chemistry; Biochemistry; Biophysics; Transmembrane domain; Amino acid; Biology; Physics; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002203299,0.0003360531,0.0004383851,0.0001187004,0.0001089546,0.00001619741,0.0003842505,0.0002381244,0.00002035994],"category_scores_gemma":[0.00001374565,0.0002530473,0.0002296482,0.0003079326,0.0004972341,0.00001720809,0.00008460195,0.0001268437,0.000002146616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009687779,"about_ca_system_score_gemma":0.00007277153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006595645,"about_ca_topic_score_gemma":0.0001076068,"domain_scores_codex":[0.998143,0.0001149289,0.0005937497,0.0005279527,0.0003019606,0.0003184273],"domain_scores_gemma":[0.9988123,0.00002662015,0.0003321845,0.0005881895,0.0001512493,0.00008947711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004011772,0.000751027,0.0003814002,0.0001563593,0.0001888199,0.000001152337,0.000705042,0.00003733331,0.9966005,0.00003596754,0.00003152404,0.0007097088],"study_design_scores_gemma":[0.001352618,0.0004543726,0.01875219,0.00005203287,0.0001572346,0.000007621504,0.000255599,0.0001097009,0.9782571,0.00001752982,0.0003099957,0.0002739992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978145,0.0003630698,0.00002667822,0.0008382896,0.0002066104,0.0005836567,0.00009831764,0.0000197666,0.00004912469],"genre_scores_gemma":[0.9986048,0.0005384465,0.0001136833,0.000145991,0.0002089004,0.00001840073,0.0001599351,0.00004018705,0.000169621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01837079,"threshold_uncertainty_score":0.9999922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008319338759432604,"score_gpt":0.2336848092871431,"score_spread":0.2253654705277105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}