{"id":"W2040504471","doi":"10.4236/eng.2012.410b009","title":"Anticancer Gene-engineered MSC-mediated Cancer Cell Death: An Imaging Demonstration","year":2012,"lang":"en","type":"article","venue":"Engineering","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"PTEN; Mesenchymal stem cell; Cancer research; Transfection; Cancer cell; Intracellular; Cell; Biology; Cancer; Chemistry; Gene; Cell biology; Signal transduction; PI3K/AKT/mTOR pathway; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003096968,0.0001892307,0.0002182101,0.0001128044,0.00004688734,0.00002759065,0.0000910209,0.00007422679,0.0005068446],"category_scores_gemma":[0.00009176225,0.0001822241,0.00005407493,0.0002245127,0.0000140317,0.0003927556,0.00002992048,0.0002611155,0.00007243954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002689536,"about_ca_system_score_gemma":0.00008357262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002054207,"about_ca_topic_score_gemma":0.000009318875,"domain_scores_codex":[0.9985024,0.00001922247,0.0002243176,0.0002143439,0.0003819532,0.0006577866],"domain_scores_gemma":[0.9990658,0.00007089219,0.00002865018,0.000269622,0.00007847478,0.0004866278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002019084,0.00009618659,0.07818318,0.0001908021,0.00003583914,0.0000349686,0.0003879186,0.00258321,0.9163456,0.00009857652,0.0001498052,0.001873702],"study_design_scores_gemma":[0.001386096,0.00008227021,0.1968201,0.0001731154,0.000112809,0.0001121944,0.0001633201,0.3897285,0.4049452,0.000001814033,0.005916651,0.0005578218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806745,0.004910473,0.01092482,0.0001047204,0.0004726135,0.000326992,0.000009893762,0.0002442219,0.002331785],"genre_scores_gemma":[0.9936793,0.0002475655,0.004792978,0.00005139759,0.0007671127,0.0000562061,0.00004651122,0.00006443883,0.0002944698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5114004,"threshold_uncertainty_score":0.7430883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02766124802597841,"score_gpt":0.3004682015681116,"score_spread":0.2728069535421332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}