{"id":"W2040504471","doi":"10.4236/eng.2012.410b009","title":"Anticancer Gene-engineered MSC-mediated Cancer Cell Death: An Imaging Demonstration","year":2012,"lang":"en","type":"article","venue":"Engineering","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"PTEN; Mesenchymal stem cell; Cancer research; Transfection; Cancer cell; Intracellular; Cell; Biology; Cancer; Chemistry; Gene; Cell biology; Signal transduction; PI3K/AKT/mTOR pathway; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001465261,0.0002996229,0.0001642924,0.0001840585,0.0001258447,0.0002067928,0.0002288433,0.0003211296,0.0006454739],"category_scores_gemma":[0.0001052918,0.00009562368,0.000154766,0.0001137716,0.0001800821,0.0002100024,0.000172304,0.0003595121,0.000263697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002083629,"about_ca_system_score_gemma":0.0002417621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006795016,"about_ca_topic_score_gemma":0.0005142917,"domain_scores_codex":[0.9999255,0.00000994688,0.000003699475,0.00001412528,0.00002982327,0.00001698799],"domain_scores_gemma":[0.9999244,0.0000221279,0.00001657175,0.000008509363,0.00001707116,0.00001130687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002062136,0.00001176789,0.00006008008,0.00002346934,0.000001735625,0.00009918879,0.00002333906,0.00007892093,0.9980101,0.0003062584,0.00002427135,0.00134025],"study_design_scores_gemma":[0.00000292995,0.00004016599,0.0001637046,0.000001352947,0.000003246523,0.0001484301,0.000005650886,0.000786517,0.9980908,0.00002137484,0.0007345158,0.000001208237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9468906,0.001880609,0.04553962,0.0002322198,0.0000372201,0.0000780966,0.0001859559,0.0001796725,0.004976036],"genre_scores_gemma":[0.9783909,0.001094944,0.01772522,0.00005094602,0.00001111468,0.00005099137,0.0001363694,0.00003259152,0.002507014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006795016,"threshold_uncertainty_score":0.002159357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02766124802597841,"score_gpt":0.3004682015681116,"score_spread":0.2728069535421332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}