{"id":"W2040540600","doi":"10.1016/j.pharmthera.2007.03.014","title":"Potassium channel diversity in the pulmonary arteries and pulmonary veins: Implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension","year":2007,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Hypoxic pulmonary vasoconstriction; Pulmonary hypertension; High-altitude pulmonary edema; Potassium channel; Hypoxia (environmental); Pulmonary artery; Inward-rectifier potassium ion channel; Internal medicine; Vascular resistance; Lung; Biology; Cardiology; Endocrinology; Medicine; Chemistry; Pulmonary edema; Ion channel; Hemodynamics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006118321,0.0003398253,0.0005615043,0.000202329,0.0004246244,0.00001320425,0.0002785658,0.0004888166,0.000002332984],"category_scores_gemma":[0.000008970285,0.0002408381,0.0002030868,0.0003341508,0.0002637093,0.0000197354,0.0003214057,0.0003704435,2.58586e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006721899,"about_ca_system_score_gemma":0.0001216176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001666134,"about_ca_topic_score_gemma":0.00001111156,"domain_scores_codex":[0.9980028,0.000442455,0.0005643434,0.0005159952,0.0001354597,0.0003389963],"domain_scores_gemma":[0.998993,0.0001162977,0.0004016522,0.0003331318,0.00009299377,0.00006295623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001404042,0.001944905,0.005435588,0.01316386,0.0006616454,0.00003029526,0.001035554,0.0002474477,0.04105441,0.0001937361,0.0003012232,0.9345273],"study_design_scores_gemma":[0.001322913,0.0003812113,0.1332493,0.001557497,0.001071734,0.001816379,0.0007048,0.002842753,0.0004185167,0.001007581,0.8546744,0.0009529509],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01906674,0.9759662,0.00007613215,0.002293868,0.0005986087,0.001811924,0.0001010134,0.00001344976,0.00007204619],"genre_scores_gemma":[0.2025126,0.7953291,0.00002190939,0.001138295,0.0003216005,0.0001347827,0.0003959415,0.0000346683,0.000111092],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9335743,"threshold_uncertainty_score":0.9821094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07941972703977618,"score_gpt":0.3375558442338699,"score_spread":0.2581361171940937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}